Evidence map›Paper›PMID 29736465›Full record

ReviewContemporary clinical trials communications2016

Critical appraisal of the clinical utility of sublingual immunotherapy in allergy.

S Aissa, R Ben Jazia, J Ayachi, C Ben Salem, A Hayouni, A Abdelghani, H Ben Saad, M Boussarsar

Open access · goldAbstract readReview
In one paragraph

Review in Contemporary clinical trials communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

S AissaPulmonology Department, Farhat Hached University Hospital, Sousse, 4000, Tunisia.
R Ben JaziaPulmonology Department, Farhat Hached University Hospital, Sousse, 4000, Tunisia.
J AyachiMedical Intensive Care Unit, Farhat Hached University Hospital, Sousse, Tunisia.
C Ben SalemDepartment of Clinical Pharmacology, Faculty of Medicine of Sousse, Tunisia.
A HayouniPulmonology Department, Farhat Hached University Hospital, Sousse, 4000, Tunisia.
A AbdelghaniPulmonology Department, Farhat Hached University Hospital, Sousse, 4000, Tunisia.
H Ben SaadLaboratory of Physiology, Farhat Hached University Hospital, Sousse, Tunisia.
M BoussarsarMedical Intensive Care Unit, Farhat Hached University Hospital, Sousse, Tunisia.
Hôpital Farhat Hached · TNUniversity of Sousse · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since it was introduced by Noon in 1911, allergen-specific immunotherapy or desensitization has been widely prescribed in the management of allergic diseases. Aimed at the etiology, it represents the only effective treatment for allergy. The basic mechanisms of immunotherapy are becoming better understood and allow us to improve this technique in the future. The sublingual immunotherapy as an alternative to subcutaneous route has been widely studied. Several clinical trials confirmed that sublingual immunotherapy is efficient in reducing allergic respiratory symptoms. The sublingual immunotherapy reduces the risk of developing serious side effects due to desensitization. We performed a literature review in order to remind the mechanisms of action and to demonstrate efficacy and tolerability of the sublingual immunotherapy in the treatment of allergic rhinoconjunctivitis and asthma and its impact on the quality of life.

Indexed as

Allergen specific immunotherapyAllergyAsthmaRhinoconjunctivitisSublingual immunotherapy

Identifiers

PMID29736465
PMCPMC5935903
OpenAlexW2468337581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.