Evidence map›Paper›PMID 29736296›Full record

ArticleJournal of pharmaceutical analysis2018

Physicochemical characterization, the Hirshfeld surface, and biological evaluation of two meloxicam compounding pharmacy samples.

Luciana F A Romani, Maria I Yoshida, Elionai C L Gomes, Renes R Machado, Felipe F Rodrigues, Márcio M Coelho, Marcelo A Oliveira, Maria B Freitas-Marques, Rosane A S San Gil, Wagner N Mussel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Mouse Behavior in the Open-field Test after Meloxicam Administration.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Luciana F A RomaniDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Maria I YoshidaDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Elionai C L GomesDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Renes R MachadoDepartment of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Felipe F RodriguesDepartment of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Márcio M CoelhoDepartment of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Marcelo A OliveiraHealth Science Department, Federal University of Espírito Santo, Campus São Mateus, ES, Brazil.
Maria B Freitas-MarquesDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Rosane A S San GilInstitute of Chemistry, Federal University of Rio de Janeiro, Campus Fundão, RJ, Brazil.
Wagner N MusselDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, MG, Brazil.
Universidade Federal de Minas Gerais · BRUniversidade Federal do Espírito Santo · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meloxicam (MLX) is an anti-inflammatory drug susceptible to variations and crystalline transitions. In compounding pharmacies, the complete crystallographic evaluation of the raw material is not a routine procedure. We performed a complete crystallographic characterization of aleatory raw MLX samples from compounding pharmacies. X-ray diffraction indicated the presence of two crystalline forms in one sample. DSC experiments suggested that crystallization, or a crystal transition, occurred differently between samples. The FTIR and

Indexed as

Anti-inflammatory activityHirshfeld surfaceMeloxicamPolymorphism

Identifiers

PMID29736296
PMCPMC5934743
OpenAlexW2778864926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.