Evidence map›Paper›PMID 29736209›Full record

ArticleAmerican journal of translational research2018

MicroRNA-214 inhibits the proliferation and invasion of lung carcinoma cells by targeting JAK1.

Xiaofeng Chen, Jiangyuan Du, Rui Jiang, Ling Li

Abstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Alkaloid Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. MicroRNA Dysregulation in Cutaneous Squamous Cell Carcinoma.International journal of molecular sciences · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiaofeng ChenDepartment of Oncology, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Jiangyuan DuCancer Institute, Fudan University Shanghai Cancer, Department of Oncology, Shanghai Medical College, Fudan University Shanghai 200433, China.
Rui JiangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center Shanghai 200032, China.
Ling LiDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center Shanghai 200032, China.
Fudan University Shanghai Cancer Center · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence suggests that microRNAs (miRNAs) play a crucial role in the pathogenesis of tumor. In this study, miR-214 was found to be significantly down-regulated in lung tumor tissues and lung cell lines. From the gain-of-function experiment results, we found that ectopic expression of miR-214 in lung cancer cell lines significantly inhibited cell growth, as evidenced by cell viability and colony formation assays, and suppressed tumor growth in

Indexed as

JAK1lung cancermiR-214tumor suppressor

Identifiers

PMID29736209
PMCPMC5934575
OpenAlexW2962920997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.