Evidence map›Paper›PMID 29735757›Full record

ArticleJournal of bacteriology2018

Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing.

Jennifer R Klaus, Jacqueline Deay, Benjamin Neuenswander, Wyatt Hursh, Zhe Gao, Tiffany Bouddhara, Todd D Williams, Justin Douglas, Kyle Monize, Patricia Martins and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Frontiers in microbiology · 2024
    Article
  5. Biofilm Signaling, Composition and Regulation inJournal of microbiology and biotechnology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Methodological tools to study species of the genus Burkholderia.Applied microbiology and biotechnology · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Chimeric LuxR Transcription Factors Rewire Natural Product Regulation.Angewandte Chemie (International ed. in English) · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Jennifer R KlausDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Jacqueline DeayDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Benjamin NeuenswanderChemical Methodologies and Library Development Legacy, University of Kansas, Lawrence, Kansas, USA.
Wyatt HurshDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Zhe GaoDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas, USA.
Tiffany BouddharaDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Todd D WilliamsMass Spectrometry and Analytical Proteomics Laboratory, University of Kansas, Lawrence, Kansas, USA.
Justin DouglasNuclear Magnetic Resonance Core Laboratory, University of Kansas, Lawrence, Kansas, USA.
Kyle MonizeDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Patricia MartinsDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Charlotte MajerczykDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Mohammad R SeyedsayamdostDepartment of Chemistry, Princeton University, Princeton, New Jersey, USA.
Blake R PetersonDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas, USA.
Mario RiveraDepartment of Chemistry, University of Kansas, Lawrence, Kansas, USA.
Josephine R ChandlerDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA jrchandler@ku.edu.
University of Kansas · USPrinceton University · USUniversity of Washington · US

Funding

Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI PETERSON, BLAKE · 2012 to 2021
$22.1M
U of Kansas/Haskell Indian Nations U.IRACDA ProjectK12GM063651 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI DE GUZMAN, ROBERTO N · 2002 to 2022
$10.0M
Synthetic Lethal Targeting of Growth Factor ReceptorsR01CA211720 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI PETERSON, BLAKE · 2017 to 2021
$1.7M
Legacy continuation of the KU CMLD MissionR24GM111385 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI PRISINZANO, THOMAS EDWARD · 2014 to 2016
$1.5M
Chemical tools for perturbing iron homeostasis in P. aeruginosaR01AI125529 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI RIVERA, MARIO · 2016 to 2019
$1.4M
Avance II 500 High Performance Digital NMR Spectrometer SystemS10RR024664 · NCRR · UNIVERSITY OF KANSAS LAWRENCE · PI VANDERVELDE, DAVID G · 2007 to 2007
$468k
NCI NIH HHS R01 CA211720NCRR NIH HHS S10 RR024664NIAID NIH HHS R01 AI125529NIGMS NIH HHS K12 GM063651NIGMS NIH HHS P20 GM103638NIGMS NIH HHS R24 GM111385
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

A549 CellsAnimalsAnti-Bacterial AgentsBacterial ProteinsBurkholderia pseudomalleiCaenorhabditis elegansGene Expression Regulation, BacterialHumansJurkat CellsLactonesQuorum SensingVirulenceVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsLactonesmalleilactoneVirulence FactorsBurkholderiapolyketidequorum sensing

Identifiers

PMID29735757
PMCPMC6018353
OpenAlexW2801915295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.