ArticleProceedings of the National Academy of Sciences of the United States of America2018
Wireless, intraoral hybrid electronics for real-time quantification of sodium intake toward hypertension management.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed, 174 citations in OpenAlex.
- Review
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- Biosensors in dental, oral and craniofacial applications.Npj biosensing · 2026Review
- A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Wearable biomolecular sensing nanotechnologies in chronic disease management.Nature nanotechnology · 2025Review
- Implantable bioelectronics and wearable sensors for kidney health and disease.Nature reviews. Nephrology · 2025Review
- Recent Advancements and Applications of Nanosensors in Oral Health: Revolutionizing Diagnosis and Treatment.European journal of dentistry · 2025Article
- Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies.Biosensors · 2025Review
- The Role of Wearable Devices in Blood Pressure Monitoring and Hypertension Management: A Systematic Review.Cureus · 2024Review
- Beyond Flexible: Unveiling the Next Era of Flexible Electronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Large-scale smart bioreactor with fully integrated wireless multivariate sensors and electronics for long-term in situ monitoring of stem cell culture.Science advances · 2024Article
- Advances and Opportunities of Mobile Health in the Postpandemic Era: Smartphonization of Wearable Devices and Wearable Deviceization of Smartphones.JMIR mHealth and uHealth · 2024Article
- Salivary diagnostics: opportunities and challenges.Theranostics · 2024Review
- Methods for Assessing Health Outcomes Associated with Food Insecurity in the United States College Student Population: A Narrative Review.Advances in nutrition (Bethesda, Md.) · 2024Review
- Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation.International journal of oral science · 2023Review
- A Flexible Piezocapacitive Pressure Sensor with Microsphere-Array Electrodes.Nanomaterials (Basel, Switzerland) · 2023Article
- Peri-implant diseases diagnosis, prognosis and dental implant monitoring: a narrative review of novel strategies and clinical impact.BMC oral health · 2023Review
- Reshaping healthcare with wearable biosensors.Scientific reports · 2023Article
- A Wide-Range-Response Piezoresistive-Capacitive Dual-Sensing Breathable Sensor with Spherical-Shell Network of MWCNTs for Motion Detection and Language Assistance.Nanomaterials (Basel, Switzerland) · 2023Article
- Wearables in Nephrology: Fanciful Gadgetry or Prêt-à-Porter?Sensors (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent wearable devices offer portable monitoring of biopotentials, heart rate, or physical activity, allowing for active management of human health and wellness. Such systems can be inserted in the oral cavity for measuring food intake in regard to controlling eating behavior, directly related to diseases such as hypertension, diabetes, and obesity. However, existing devices using plastic circuit boards and rigid sensors are not ideal for oral insertion. A user-comfortable system for the oral cavity requires an ultrathin, low-profile, and soft electronic platform along with miniaturized sensors. Here, we introduce a stretchable hybrid electronic system that has an exceptionally small form factor, enabling a long-range wireless monitoring of sodium intake. Computational study of flexible mechanics and soft materials provides fundamental aspects of key design factors for a tissue-friendly configuration, incorporating a stretchable circuit and sensor. Analytical calculation and experimental study enables reliable wireless circuitry that accommodates dynamic mechanical stress. Systematic in vitro modeling characterizes the functionality of a sodium sensor in the electronics. In vivo demonstration with human subjects captures the device feasibility for real-time quantification of sodium intake, which can be used to manage hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.