Evidence map›Paper›PMID 29735685›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa.

Ola Brønstad Brynildsrud, Vegard Eldholm, Jon Bohlin, Kennedy Uadiale, Stephen Obaro, Dominique A Caugant

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  3. Ongoing Outbreak ofOpen forum infectious diseases · 2026
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  7. Frontiers in microbiology · 2025
    Article
  8. Expanding the genetic toolbox forApplied and environmental microbiology · 2024
    Article
  9. Article
  10. Genomic characterization of invasive meningococcal X isolates from Brazil, 1992-2022.International microbiology : the official journal of the Spanish Society for Microbiology · 2023
    Article
  11. Article
  12. Article
  13. Genomic surveillance of Neisseria meningitidis serogroup W in Portugal from 2003 to 2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Sudden emergence of aMicrobial genomics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ola Brønstad BrynildsrudDivision for Infection Control and Environmental Health, Norwegian Institute of Public Health, 0456 Oslo, Norway; ola.brynildsrud@fhi.no.ORCID 0000-0001-7566-4133
Vegard EldholmDivision for Infection Control and Environmental Health, Norwegian Institute of Public Health, 0456 Oslo, Norway.ORCID 0000-0001-6721-3375
Jon BohlinDivision for Infection Control and Environmental Health, Norwegian Institute of Public Health, 0456 Oslo, Norway.
Kennedy UadialeNigeria Emergency Response Unit, Médecins sans Frontières, Sokoto, Nigeria.
Stephen ObaroDivision of Pediatric Infectious Diseases, University of Nebraska Medical Center, Omaha, NE 68198.
Dominique A CaugantDivision for Infection Control and Environmental Health, Norwegian Institute of Public Health, 0456 Oslo, Norway.ORCID 0000-0003-2765-9844
Norwegian Institute of Public Health · NONigeria Centre for Disease Control · NGSokoto State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the African meningitis belt, a region of sub-Saharan Africa comprising 22 countries from Senegal in the west to Ethiopia in the east, large epidemics of serogroup A meningococcal meningitis have occurred periodically. After gradual introduction from 2010 of mass vaccination with a monovalent meningococcal A conjugate vaccine, serogroup A epidemics have been eliminated. Starting in 2013, the northwestern part of Nigeria has been affected by yearly outbreaks of meningitis caused by a novel strain of serogroup C

Indexed as

EpidemicsAfrica, WesternAntigens, BacterialGene Expression ProfilingHumansMeningitis, MeningococcalMeningococcal VaccinesNeisseria meningitidisPopulation SurveillanceSpatio-Temporal AnalysisViral ProteinsVirulenceAntigens, BacterialMeningococcal VaccinesViral Proteinshorizontal gene transfernanopore sequencingserogroup C meningococcivirulence factorswhole-genome sequencing

Identifiers

PMID29735685
PMCPMC6003489
OpenAlexW2799325619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.