Evidence map›Paper›PMID 29735665›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Ca

Rong-Chang Li, Chih-Chun Lin, Xiaozhi Ren, Jingjing Sherry Wu, Laurie L Molday, Robert S Molday, King-Wai Yau

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. The CaThe Journal of physiology · 2024
    Article
  4. Article
  5. Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. CaProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rong-Chang LiSolomon H. Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205; rongchangli@gmail.com kwyau@jhmi.edu.
Chih-Chun LinSolomon H. Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Xiaozhi RenSolomon H. Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Jingjing Sherry WuNeuroscience Graduate Program, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Laurie L MoldayDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, V6T 1Z3, Canada.
Robert S MoldayDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, V6T 1Z3, Canada.
King-Wai YauSolomon H. Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205; rongchangli@gmail.com kwyau@jhmi.edu.
Johns Hopkins University · USUniversity of British Columbia · CAJohns Hopkins Medicine · US

Funding

Cyclic AMP- and Ca2+-Signaling in Sensory Transduction by Olfactory Receptor NeuronsR01DC014941 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI KING-WAI YAU · 2016 to 2026
$3.8M
STRUCTURE/FUNCTION OF ROS PLASMA MEMBRANE PROTEINSR01EY002422 · NEI · UNIVERSITY OF BRITISH COLUMBIA · PI MOLDAY, ROBERT S · 1985 to 2017
$3.5M
NEI NIH HHS R01 EY002422NIDCD NIH HHS R01 DC014941
6 · The paper itself

Abstract

In mammalian olfactory transduction, odorants activate a cAMP-mediated signaling pathway that leads to the opening of cyclic nucleotide-gated (CNG), nonselective cation channels and depolarization. The Ca

Indexed as

AnimalsAnoctaminsBrainCalciumChloridesCyclic AMPCyclic Nucleotide-Gated Cation ChannelsMembrane PotentialsMiceMice, KnockoutOlfactory Receptor NeuronsPatch-Clamp TechniquesSignal TransductionSmellANO2 protein, mouseAnoctaminsCalciumChloridesCyclic AMPCyclic Nucleotide-Gated Cation ChannelsCa2+-activated Cl channelcyclic nucleotide-gated channelolfactory receptor neuronsolfactory transductionsignal amplification

Identifiers

PMID29735665
PMCPMC6003478
OpenAlexW2803756859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.