Evidence map›Paper›PMID 29735606›Full record

ArticleGenome research2018

Allele-specific control of replication timing and genome organization during development.

Juan Carlos Rivera-Mulia, Andrew Dimond, Daniel Vera, Claudia Trevilla-Garcia, Takayo Sasaki, Jared Zimmerman, Catherine Dupont, Joost Gribnau, Peter Fraser, David M Gilbert

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 92 citations in OpenAlex.

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  20. Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Juan Carlos Rivera-MuliaDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
Andrew DimondThe Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, United Kingdom.
Daniel VeraCenter for Genomics and Personalized Medicine, Florida State University, Tallahassee, Florida 32306, USA.
Claudia Trevilla-GarciaDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
Takayo SasakiDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
Jared ZimmermanDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
Catherine DupontDepartment of Reproduction and Development, Erasmus MC, University Medical Center, 3015GE Rotterdam, The Netherlands.
Joost GribnauDepartment of Reproduction and Development, Erasmus MC, University Medical Center, 3015GE Rotterdam, The Netherlands.
Peter FraserDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
David M GilbertDepartment of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA.
Florida State University · USErasmus MC · NLBabraham Institute · GB

Funding

Mapping Technology DevelopmentU54DK107965 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BELMONT, ANDREW STEVEN · 2015 to 2019
$8.6M
Genome Plasticity during ES Cell Differentiation to Neural LineagesR01GM083337 · NIGMS · SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE · PI David M Gilbert · 2007 to 2026
$6.1M
NIDDK NIH HHS U54 DK107965NIGMS NIH HHS R01 GM083337
6 · The paper itself

Abstract

DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization. Here, we derived distinct cell types from F1 hybrid

Indexed as

AllelesAnimalsCell DifferentiationCell LineageDNA ReplicationDNA Replication TimingFemaleFibroblastsGene Expression Regulation, DevelopmentalGenomeMaleMiceMouse Embryonic Stem CellsNeural Stem CellsPromoter Regions, Genetic

Identifiers

PMID29735606
PMCPMC5991511
OpenAlexW2772621029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.