Evidence map›Paper›PMID 29735555›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Genetic Activation, Inactivation, and Deletion Reveal a Limited And Nuanced Role for Somatostatin-Containing Basal Forebrain Neurons in Behavioral State Control.

Christelle Anaclet, Roberto De Luca, Anne Venner, Olga Malyshevskaya, Michael Lazarus, Elda Arrigoni, Patrick M Fuller

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  3. Science advances · 2026
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  5. Targeted spiral ganglion neuron degeneration in parvalbumin-Cre neonatal mice.Molecular therapy. Methods & clinical development · 2025
    Article
  6. Distinct Patterns of PV and SST GABAergic Neuronal Activity in the Basal Forebrain during Olfactory-Guided Behavior in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neuronal PAS domain 1 identifies a major subpopulation of wakefulness-promoting GABAergic neurons in the basal forebrain.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Neural Control of REM Sleep and Motor Atonia: Current Perspectives.Current neurology and neuroscience reports · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christelle AnacletDepartment of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115.
Roberto De LucaDepartment of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115.ORCID 0000-0001-8105-426X
Anne VennerDepartment of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115.ORCID 0000-0001-7481-3248
Olga MalyshevskayaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.ORCID 0000-0002-7454-0195
Michael LazarusInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.ORCID 0000-0003-3863-4474
Elda ArrigoniDepartment of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115, earrigon@bidmc.harvard.edu pfuller@bidmc.harvard.edu.ORCID 0000-0002-4391-6700
Patrick M FullerDepartment of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115, earrigon@bidmc.harvard.edu pfuller@bidmc.harvard.edu.ORCID 0000-0002-7017-583X
Beth Israel Deaconess Medical Center · USUniversity of Tsukuba · JP

Funding

Molecular-Genetic Dissection of Subcortical Circuitry Regulating ArousalR01NS073613 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Patrick M Fuller · 2011 to 2026
$5.5M
Brainstem regulation of sleepR01NS092652 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FULLER, PATRICK M · 2015 to 2019
$2.2M
Basal forebrain hypothalamic networks supporting wakefulnessR01NS091126 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ARRIGONI, ELDA · 2015 to 2019
$1.9M
Dissection of a novel inhibitory hypothalamic arousal circuitR01NS103161 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FULLER, PATRICK M · 2017 to 2021
$1.9M
Medullary Circuitry Regulating Slow-Wave-SleepR00MH103399 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ANACLET, CHRISTELLE · 2017 to 2019
$742k
Medullary Circuitry Regulating Slow-Wave-SleepK99MH103399 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANACLET, CHRISTELLE · 2014 to 2015
$167k
NIMH NIH HHS K99 MH103399NIMH NIH HHS R00 MH103399NINDS NIH HHS R01 NS073613NINDS NIH HHS R01 NS091126NINDS NIH HHS R01 NS092652NINDS NIH HHS R01 NS103161
6 · The paper itself

Abstract

Recent studies have identified an especially important role for basal forebrain GABAergic (BF

Indexed as

AnimalsBasal ForebrainBehavior, AnimalElectroencephalographyElectrophysiological PhenomenaFemaleGene DeletionGenotypeMaleMiceNeuronsOptogeneticsSleep, Slow-WaveSomatostatinTranscriptional ActivationVesicular Inhibitory Amino Acid Transport ProteinsSomatostatinVesicular Inhibitory Amino Acid Transport ProteinsViaat protein, mouseAAVarousaldiphtheriaDREADDEEGoptogenetic

Identifiers

PMID29735555
PMCPMC5977448
OpenAlexW2800356052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.