Evidence map›Paper›PMID 29735495›Full record

ArticleBMJ case reports2018

Anaesthetic management of a patient with a unique combination of anti-N-methyl-D-aspartate receptor encephalitis and stiff-person syndrome.

Mohammad Hadi Gharedaghi, Arjang Khorasani, Nebojsa Nick Knezevic, Farzad Ebrahimi

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Postoperative hypotonia in a patient with stiff person syndrome: a case report and literature review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mohammad Hadi GharedaghiDepartment of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.
Arjang KhorasaniDepartment of Anesthesiology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA.
Nebojsa Nick KnezevicDepartment of Anesthesiology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA.
Farzad EbrahimiDepartment of Anesthesiology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0002-3960-451X
University of Illinois Chicago · USAdvocate Illinois Masonic Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stiff-person syndrome (SPS) and anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis are rare paraneoplastic syndromes caused by antibodies that target the central nervous system. Here, we describe a 26-year-old woman who presented with psychosis, amnesia, rigidity and fever. After extensive diagnostic and laboratory workup, she was diagnosed with an ovarian teratoma which was causing the symptoms of anti-NMDAR encephalitis and SPS. The patient was successfully treated with laparoscopic removal of the ovarian tumour under general anaesthesia. She was placed on immunosuppressant medications preoperatively and postoperatively, and her symptoms gradually resolved. Although there are case reports regarding the anaesthetic management of SPS and anti-NMDAR encephalitis, our study is the first report of a patient afflicted with both conditions.

Indexed as

Administration, IntravenousAdultAnesthesia, GeneralAnestheticsAnti-N-Methyl-D-Aspartate Receptor EncephalitisAutoantibodiesFemaleHumansImmunosuppressive AgentsLaparoscopyOvarian NeoplasmsParaneoplastic SyndromesPropofolReceptors, N-Methyl-D-AspartateStiff-Person SyndromeTeratomaAnestheticsAutoantibodiesImmunosuppressive AgentsPropofolReceptors, N-Methyl-D-Aspartateanaesthesiagynecological cancer

Identifiers

PMID29735495
PMCPMC5950572
OpenAlexW2799492095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.