Evidence map›Paper›PMID 29735480›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Comparative Transcriptomic Response of Primary and Immortalized Macrophages to Murine Norovirus Infection.

Eric A Levenson, Craig Martens, Kishore Kanakabandi, Charles V Turner, Kimmo Virtaneva, Monica Paneru, Stacy Ricklefs, Stanislav V Sosnovtsev, Jordan A Johnson, Stephen F Porcella and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
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  4. Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.Frontiers in cellular and infection microbiology · 2025
    Article
  5. Article
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  7. Antioxidants (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Eric A LevensonCaliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and kgreen@niaid.nih.gov eric.levenson@nih.gov.ORCID 0000-0002-3896-3908
Craig MartensRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Kishore KanakabandiRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.ORCID 0000-0003-3259-4459
Charles V TurnerRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Kimmo VirtanevaRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.ORCID 0000-0002-5503-1483
Monica PaneruRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.ORCID 0000-0001-8594-4980
Stacy RicklefsRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Stanislav V SosnovtsevCaliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.
Jordan A JohnsonCaliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.
Stephen F PorcellaRocky Mountain Laboratories Genomics Unit, Research Technologies Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.ORCID 0000-0001-5512-1553
Kim Y GreenCaliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and kgreen@niaid.nih.gov eric.levenson@nih.gov.ORCID 0000-0002-8189-7352
National Institutes of Health · US

Funding

Infectious Diseases Research Technologies Core - RMLZICAI001052 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$133.3M
Noroviruses and Epidemic GastroenteritisZIAAI000897 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GREEN, KIM Y. · 2009 to 2025
$29.6M
Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

Murine norovirus (NoV) is genetically similar to human NoV and offers both an efficient in vitro cell culture system and an animal model by which to investigate the molecular basis of replication. In this study, we present a detailed global view of host alterations to cellular pathways that occur during the progression of a NoV infection. This was accomplished for both

Indexed as

AnimalsCaliciviridae InfectionsCell CycleCell LineDNA ReplicationInterferon-betaInterferon Regulatory Factor-3Interferon Regulatory Factor-7MacrophagesMiceMice, Inbred BALB CNorovirusRAW 264.7 CellsTranscription, GeneticTranscriptomeInterferon-betaInterferon Regulatory Factor-3Interferon Regulatory Factor-7

Identifiers

PMID29735480
PMCPMC5988982
OpenAlexW2802757427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.