ArticleKidney international2018
Factors leading to the discard of deceased donor kidneys in the United States.
Article in Kidney international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
112 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Time-Zero Kidney Biopsy and Deceased-Donor Transplant Outcomes: A Systematic Review and Meta-Analysis of Prognostic Value, Prediction, and Clinical Utility.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Kidney Transplantation From Donors With Acute Kidney Injury: Are the Concerns Justified? A Systematic Review and Meta-Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2023Pooled it
- The utility of machine learning for predicting donor non-use in lung transplantation.JHLT open · 2026Article
- From Determination of Death by Neurological Criteria to Early Graft Function: A 7-Year Single-Center Retrospective Study of 155 Consecutive Cases.Clinical transplantation · 2026Observational
- Quantitative Assessment of Kidney Interstitial Fibrosis Using Optical Spectroscopy Mediated through a Fine Needle Probe.Kidney360 · 2026Article
- CRISPR-based ex vivo gene editing of donor organs.Nature reviews bioengineering · 2026Article
- Impact of older donor age in kidney transplants in a biopsy-based observational study.JCI insight · 2026Observational
- Rethinking procurement biopsy in donors with normal renal function: A barrier to kidney utilization without survival benefit.World journal of transplantation · 2026Article
- Influence of Hypothermic Machine Perfusion on Markers of Oxidative Stress and Early Tubular Injury in Rat Donor Kidneys Before Transplantation.Kidney and dialysis · 2026Article
- Impact of Cold Ischemia Time on Allograft Survival and Policy.Kidney international reports · 2026Article
- Single-kidney transplantation with discarded partner kidney vs. Dual kidney transplantation: results from a national cohort study.BMC nephrology · 2026Article
- Development of a Donor-Based Predictive Model for Pancreas Non-Utilization Among Deceased Donor Transplants in the US.Clinical transplantation · 2026Article
- How Far Is a Kidney Willing to Go? Kidney Transplant Outcomes Based on Distance Donor Kidney Travels to Transplant Centers.Kidney medicine · 2026Article
- Impact of donor's acute kidney injury on graft outcomes of deceased donor kidney transplantation.Scientific reports · 2026Article
- Proteinuria in Deceased Diabetic Donors and Kidney Transplant Outcomes.Canadian journal of kidney health and disease · 2026Article
- Revealing the potential of non-transplanted donor organs: a comparative analysis in the Eurotransplant region.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Superior transplant recipient outcome prediction and pathology assessment using rapid deep learning applied to procurement kidney biopsies.Scientific reports · 2025Article
- Donor kidney pathology combined with clinical parameters helps expand the kidney donor pool: a large-scale retrospective cohort study.Renal failure · 2025Article
- Adult Dual Kidney Transplantation Following Dual Renal Endarterectomy: A Case Series.Clinical transplantation · 2025Article
- Utilization of Pediatric En Bloc Kidneys from Donation After Cardio-Circulatory Determination of Death: 15 Years of Experience.Clinical transplantation · 2025Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The proportion of deceased donor kidneys procured for transplant but subsequently discarded has been growing steadily in the United States, but factors contributing to the rising discard rate remain unclear. To assess the reasons for and probability of organ discard we assembled a cohort of 212,305 deceased donor kidneys recovered for transplant from 2000-2015 in the SRTR registry that included 36,700 kidneys that were discarded. 'Biopsy Findings' (38.2%) was the most commonly reported reason for discard. The median Kidney Donor Risk Index of discarded kidneys was significantly higher than transplanted organs (1.78 vs 1.12), but a large overlap in the quality of discarded and transplanted kidneys was observed. Kidneys of donors who were older, female, Black, obese, diabetic, hypertensive or HCV-positive experienced a significantly increased odds of discard. Kidneys from donors with multiple unfavorable characteristics were more likely to be discarded, whereas unilaterally discarded kidneys had the most desirable donor characteristics and the recipients of their partner kidneys experienced a one-year death-censored graft survival rate over 90%. There was considerable geographic variation in the odds of discard across the United States, which further supports the notion that factors beyond organ quality contributed to kidney discard. Thus, while the discard of a small fraction of organs procured from donors may be inevitable, the discard of potentially transplantable kidneys needs to be avoided. This will require a better understanding of the factors contributing to organ discard in order to remove the disincentives to utilize less-than-ideal organs for transplantation.
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