Evidence map›Paper›PMID 29734959›Full record

ArticleEpidemiology and infection2018

Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia.

M J Lydeamore, P T Campbell, W Cuningham, R M Andrews, T Kearns, D Clucas, R Gundjirryirr Dhurrkay, J Carapetis, S Y C Tong, J M McCaw and 1 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M J LydeamoreSchool of Mathematics and Statistics,The University of Melbourne,Parkville,Victoria,Australia.ORCID 0000-0001-6515-827X
P T CampbellMurdoch Children's Research Institute,The Royal Children's Hospital,Melbourne,Victoria,Australia.ORCID 0000-0003-4013-9835
W CuninghamVictorian Infectious Diseases Reference Laboratory Epidemiology Unit,Peter Doherty Institute for Infection and Immunity,The Royal Melbourne Hospital and The University of Melbourne,Melbourne,Victoria,Australia.ORCID 0000-0001-5404-6088
R M AndrewsMenzies School of Health Research,Charles Darwin University,Darwin,Casuarina,Australia.
T KearnsMenzies School of Health Research,Charles Darwin University,Darwin,Casuarina,Australia.
D ClucasClinical Haematology,The Alfred Hospital and Monash Medical Centre,Melbourne,Victoria,Australia.
R Gundjirryirr DhurrkayMenzies School of Health Research,Charles Darwin University,Darwin,Casuarina,Australia.
J CarapetisTelethon Kids Institute,University of Western Australia and Princess Margaret Hospital for Children,Perth,Western Australia.
S Y C TongNational Centre for Epidemiology & Population Health,Australian National University,Canberra,Australia.ORCID 0000-0002-1368-8356
J M McCawSchool of Mathematics and Statistics,The University of Melbourne,Parkville,Victoria,Australia.ORCID 0000-0002-2452-3098
J McVernonMurdoch Children's Research Institute,The Royal Children's Hospital,Melbourne,Victoria,Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models. To estimate the force of infection, we quantified the age of first skin sores and scabies infection by pooling historical data from three studies conducted across five remote Aboriginal communities for children born between 2001 and 2005. We estimated the age of the first infection using the Kaplan-Meier estimator; parametric exponential mixture model; and Cox proportional hazards. For skin sores, the mean age of the first infection was approximately 10 months and the median was 7 months, with some heterogeneity in median observed by the community. For scabies, the mean age of the first infection was approximately 9 months and the median was 8 months, with significant heterogeneity by the community and an enhanced risk for children born between October and December. The young age of the first infection with skin sores and scabies reflects the high disease burden in these communities.

Indexed as

Rural HealthStreptococcus pyogenesAge FactorsChild, PreschoolCost of IllnessFemaleFollow-Up StudiesHumansInfantInfant, NewbornKaplan-Meier EstimateMaleModels, BiologicalNorthern TerritoryPrevalenceProportional Hazards Modelsaboriginal healthage of first infectionnorthern territoryscabiesSkin Sores

Identifiers

PMID29734959
PMCPMC9134287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.