Evidence map›Paper›PMID 29734775›Full record

ArticleViruses2018

Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9.

Jinxin Miao, Baoling Ying, Rong Li, Ann E Tollefson, Jacqueline F Spencer, William S M Wold, Seok-Hwan Song, Il-Keun Kong, Karoly Toth, Yaohe Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
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  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. The CRISPR journal · 2020
    Article
  13. Article
  14. Generation and characterization of anDisease models & mechanisms · 2020
    Article
  15. Article
  16. A NovelFrontiers in genetics · 2019
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Jinxin MiaoDepartment of Pathology, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China. jinxin.miao@yahoo.com.ORCID 0000-0003-1688-3066
Baoling YingDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. baoling.ying@health.slu.edu.
Rong LiDepartment of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. lirong14@gmail.com.ORCID 0000-0002-9638-3493
Ann E TollefsonDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. ann.tollefson@health.slu.edu.
Jacqueline F SpencerDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. jacqueline.spencer@health.slu.edu.
William S M WoldDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. bill.wold@health.slu.edu.
Seok-Hwan SongDepartment of Animal Science, Division of Applied Life Science (BK21Plus), Graduate School of Gyeongsang National University, Jinju 52828, Korea. siwd2002@gmail.com.
Il-Keun KongDepartment of Animal Science, Division of Applied Life Science (BK21Plus), Graduate School of Gyeongsang National University, Jinju 52828, Korea. ikong7900@gmail.com.
Karoly TothDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. karoly.toth@health.slu.edu.
Yaohe WangDepartment of Pathology, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China. yaohe.wang@qmul.ac.uk.
Zhongde WangDepartment of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. zonda.wang@usu.edu.
Saint Louis University · USUtah State University · USGyeongsang National University · KRQueen Mary University of London · GB

Funding

Development of a STAT2 knock-out hamster model for wild-type filovirus infectionsR41OD021979 · OD · AURATUS BIO, LLC · PI ROBL, JAMES M, WANG, ZHONGDE · 2016 to 2016
$221k
NIAID NIH HHS HHSN272201000021CNIAID NIH HHS HHSN272201000021INIH HHS R41 OD021979
6 · The paper itself

Abstract

The accumulating evidence demonstrates that Syrian hamsters have advantages as models for various diseases. To develop a Syrian hamster (

Indexed as

Adenoviridae InfectionsAdenoviruses, HumanAnimalsB-LymphocytesCRISPR-Cas SystemsDisease Models, AnimalFrameshift MutationGenes, RAG-1Immunologic Deficiency SyndromesKiller Cells, NaturalMesocricetusSpleenT-Lymphocytesadenovirus infectionanimal modelCRISPR/Cas9RAG1SCIDSyrian hamster

Identifiers

PMID29734775
PMCPMC5977236
OpenAlexW2799692280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.