ArticleInternational journal of environmental research and public health2018
Trends in the Prevalences of Selected Birth Defects in Korea (2008⁻2014).
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Environmental and Genetic Risk Factors of Congenital Anomalies: an Umbrella Review of Systematic Reviews and Meta-Analyses.Journal of Korean medical science · 2021Pooled it
- Article
- Fetal malformations in women with pregestational diabetes mellitus based on pre-pregnancy fasting plasma glucose levels.Scientific reports · 2025Article
- A surveillance-based epidemiological study of renal agenesis in 25 million births in china, 2007-2020.BMC pregnancy and childbirth · 2025Article
- Incidence of neural tube defects in tertiary care university hospital in Bangladesh.Clinical and experimental pediatrics · 2025Article
- Prevalence of congenital cryptorchidism in China: A nationwide population-based surveillance study, 2007-2021.Andrology · 2025Article
- Neurodevelopmental outcomes among children with congenital gastrointestinal anomalies using Korean National Health Insurance claims data.Scientific reports · 2024Article
- Prevalence and death rate of birth defects from population-based surveillance in Hunan Province, China, 2010-2020.Scientific reports · 2024Article
- Psychosocial needs and outcomes of adults with spina bifida: A scoping review, 1974-2023.Health care transitions · 2024Article
- Update from a cohort study for birth defects in Hunan Province, China, 2010-2020.Scientific reports · 2023Article
- Optimal Protocols and Management of Clinical and Genomic Data Collection to Assist in the Early Diagnosis and Treatment of Multiple Congenital Anomalies.Children (Basel, Switzerland) · 2023Article
- Major Congenital Anomalies in Korean Livebirths in 2013-2014: Based on the National Health Insurance Database.Journal of Korean medical science · 2023Article
- Epidemiology of birth defects in a national hospital-based birth defect surveillance spot in Southern Jiangsu, China, 2014-2018.Frontiers in medicine · 2023Article
- Reducing Birth Defects by Decreasing the Prevalence of Maternal Chronic Diseases-Evaluated by Linked National Registration Dataset.Children (Basel, Switzerland) · 2022Article
- Prenatal Exposure to Alcohol, Tobacco, and Coffee: Associated Congenital Complications and Adverse Birth Outcomes.International journal of environmental research and public health · 2021Article
- Prevalence and patterns of birth defects among newborns in southwestern Ethiopia: a retrospective study.The Pan African medical journal · 2021Article
- Observational
- The birth prevalence of selected major congenital anomalies: Six-year's experience in a tertiary care maternity hospital.Turk pediatri arsivi · 2020Article
- Hypospadias Risk from Maternal Residential Exposure to Heavy Metal Hazardous Air Pollutants.International journal of environmental research and public health · 2019Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little information is available on the prevalences of birth defects in Korea. The aims of this study were to estimate recent prevalences of selected birth defects and to analyze the prevalence trends of these defects during the period from 2008 to 2014. Prevalences were calculated for 69 major birth defects using health insurance claim data obtained from the Korea National Health Insurance Service (NHIS). Prevalence rate ratios were calculated using Poisson regression to analyze trends over the 7-year study period. The overall prevalence of a major birth defect was 446.3 per 10,000 births (95% CI: 444.0⁻448.6); 470.9 per 10,000 births (95% CI: 467.6⁻474.2) for males and 420.2 per 10,000 births (95% CI: 417⁻423.4) for females. The prevalence rates of the most common birth defects over the study period were; septal defect (138.2 per 10,000; 95% CI: 136.9⁻139.5), congenital hip dislocation (652 per 10,000; 95% CI: 64.1⁻65.9), and ventricular septal defect (62.62 per 10,000; 95% CI: 61.7⁻63.5). During the study period, a significant increase in the prevalence of a major birth defect was observed with a prevalence rate ratio (PRR) of 1.091. The strongest trend was observed for renal dysplasia, which had a PRR of 1.275 (95% CI: 1.211⁻1.343), and upward trends were observed for urogenital anomalies, such as, renal agenesis (PRR 1.102, 95% CI: 1.067⁻1.138), undescended testis (PRR 1.082, 95% CI: 1.072⁻1.093) and hypospadias (PRR 1.067, 95% CI: 1.044⁻1.090). This study shows an overall increase in the prevalences of birth defects, including hypospadias and undescended testis, which are known to be associated with endocrine factors. In the future, standardized birth defect registries should be established to enable these trends to be monitored.
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