Evidence map›Paper›PMID 29734739›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis of New Glycosylated Flavonoids with Inhibitory Activity on Cell Growth.

Ana R Neves, Marta Correia-da-Silva, Patrícia M A Silva, Diana Ribeiro, Emília Sousa, Hassan Bousbaa, Madalena Pinto

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ana R NevesLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. anarcneves92@gmail.com.ORCID 0000-0002-2766-8436
Marta Correia-da-SilvaLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. m_correiadasilva@ff.up.pt.
Patrícia M A SilvaCESPU, Institute of Research and Advanced Training in Health Sciences and Technologies (IINFACTS), Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal. patricia_masilva@hotmail.com.ORCID 0000-0002-0694-7321
Diana RibeiroCESPU, Institute of Research and Advanced Training in Health Sciences and Technologies (IINFACTS), Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal. dianaroberta@ua.pt.
Emília SousaLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. esousa@ff.up.pt.ORCID 0000-0002-5397-4672
Hassan BousbaaInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N 4450-208 Matosinhos, Portugal. hassan.bousbaa@iucs.cespu.pt.ORCID 0000-0002-4006-5779
Madalena PintoLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. madalena@ff.up.pt.ORCID 0000-0002-4676-1409
Universidade do Porto · PTCooperativa de Ensino Superior Politécnico e Universitário · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural flavonoids and xanthone glycosides display several biological activities, with the glycoside moiety playing an important role in the mechanism of action of these metabolites. Herein, to give further insights into the inhibitory activity on cell growth of these classes of compounds, the synthesis of four flavonoids (

Indexed as

Acetic AnhydridesAcetylationAntineoplastic AgentsAstrocytesCell Line, TumorCell SurvivalDrug DesignEpithelial CellsFlavonoidsGlycosylationHumansInhibitory Concentration 50MCF-7 CellsMicrowavesNeurogliaStructure-Activity Relationshipacetic anhydrideAcetic AnhydridesAntineoplastic AgentsFlavonoidsxanthoneXanthonesacetylationflavonoidsglycosylationgrowth inhibitory activityxanthones

Identifiers

PMID29734739
PMCPMC6102538
OpenAlexW2801431410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.