Evidence map›Paper›PMID 29734499›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Blood perfusion of patellar bone measured by dynamic contrast-enhanced MRI in patients with patellofemoral pain: A case-control study.

Rianne A van der Heijden, Dirk H J Poot, Melek Ekinci, Gyula Kotek, Peter L J van Veldhoven, Stefan Klein, Jan A N Verhaar, Gabriel P Krestin, Sita M A Bierma-Zeinstra, Marienke van Middelkoop and 1 more

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rianne A van der HeijdenDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Dirk H J PootBiomedical Imaging Group Rotterdam, Departments of Medical Informatics & Radiology, Erasmus MC, Rotterdam, The Netherlands.
Melek EkinciDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Gyula KotekDepartment of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Peter L J van VeldhovenDepartment of Sports Medicine, Medical Center Haaglanden, Leidschendam, The Netherlands.
Stefan KleinBiomedical Imaging Group Rotterdam, Departments of Medical Informatics & Radiology, Erasmus MC, Rotterdam, The Netherlands.
Jan A N VerhaarDepartment of Orthopedics Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Gabriel P KrestinDepartment of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Sita M A Bierma-ZeinstraDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Marienke van MiddelkoopDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Edwin H G OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Funding

Dutch Arthritis FoundationErasmus University RotterdamHitachi Medical Systems/Radiological Society of North America Research Seed Grant.
6 · The paper itself

Abstract

backgroundAltered perfusion might play an important role in the pathophysiology of patellofemoral pain (PFP), a common knee complaint with unclear pathophysiology. PURPOSE: To investigate differences in dynamic contrast-enhanced (DCE)-MRI perfusion parameters between patients with PFP and healthy control subjects. POPULATION/SUBJECTS/PHANTOM/SPECIMEN/ANIMAL MODEL: Thirty-five adult patients with PFP and 44 healthy adult control subjects. FIELD STRENGTH/SEQUENCE: 3T DCE-MRI consisting of a sagittal, anterior-posterior, frequency-encoded, fat-suppressed 3D spoiled gradient-echo sequence with intravenous contrast administration. ASSESSMENT: Patellar bone volumes of interest (VOIs) were delineated by a blinded observer. Quantitative perfusion parameters (k STATISTICAL TESTS: Differences in patellar bone perfusion parameters were compared between groups by linear regression analyses, adjusted for confounders.

resultsMean differences of weighted mean and unweighted median were 0.0039 (95% confidence interval [CI] -0.0013; 0.0091) and 0.0052 (95% CI -0.0078; 0.018) for k DATA

conclusionHigher patellar bone perfusion parameters were found in patients with PFP when compared to healthy control subjects, but these differences were not statistically significant. This result, and the observed significant difference in k LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2018;47:1344-1350.

Indexed as

Magnetic Resonance ImagingAdolescentAdultCase-Control StudiesContrast MediaFemurHumansImage Processing, Computer-AssistedImaging, Three-DimensionalPainPatellaPerfusionYoung AdultContrast Mediakneemagnetic resonance imagingpatellapatellofemoral pain syndromeperfusion imaging

Identifiers

PMID29734499
PMCPMC6221059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.