Evidence map›Paper›PMID 29734484›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Radiomic features from pretreatment biparametric MRI predict prostate cancer biochemical recurrence: Preliminary findings.

Rakesh Shiradkar, Soumya Ghose, Ivan Jambor, Pekka Taimen, Otto Ettala, Andrei S Purysko, Anant Madabhushi

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 5 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 5 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  13. AI in Prostate MRI: A Task-Based Review.Journal of the Korean Society of Radiology · 2025
    Review
  14. Precision medicine in prostate cancer: individualized treatment through radiomics, genomics, and biomarkers.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Review
  15. Article
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  18. Review
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  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Rakesh ShiradkarDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0003-2852-3869
Soumya GhoseDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Ivan JamborDepartment of Diagnostic Radiology, University of Turku, Finland.
Pekka TaimenInstitute of Biomedicine, University of Turku, Turku, Finland.
Otto EttalaDepartment of Urology, Turku University Hospital, Turku, Finland.
Andrei S PuryskoSection of Abdominal Imaging and Nuclear Radiology Department, Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID 0000-0002-6888-0417
Anant MadabhushiDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Case Western Reserve University · USUniversity of Turku · FICleveland Clinic · USTurku University Hospital · FI

Funding

Computerized histologic image predictor of cancer outcomeR01CA202752 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FELDMAN, MICHAEL D, GANESAN, SHRIDAR · 2016 to 2020
$3.1M
Quantitative Histomorphometric Risk Classifier (QuHbIC) in HPV + Oropharyngeal CarcinomaR01CA220581 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KOYFMAN, SHLOMO, LEWIS, JAMES · 2018 to 2023
$3.1M
Computerized Histologic Risk Predictor (CHiRP) for Early Stage Lung CancersR01CA216579 · NCI · EMORY UNIVERSITY · PI FU, PINGFU, LLOYD, MARK · 2018 to 2023
$3.1M
MR Fingerprinting and Computerized Decision Support for Prostate CancerR01CA208236 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GULANI, VIKAS, PONSKY, LEE EVAN · 2017 to 2022
$3.0M
Pathology Image Informatics Platform for visualization, analysis and managementU24CA199374 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GURCAN, METIN NAFI, MADABHUSHI, ANANT · 2015 to 2019
$2.9M
Computerized morphologic-molecular predictor of progression in DCISR21CA195152 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI BADVE, SUNIL S., MADABHUSHI, ANANT · 2015 to 2016
$388k
BIOMEDICAL ENGINEERING RESEARCH FACILITIESC06RR012463 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI KUTINA, KENNETH L · 1997 to 1997
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DOD Peer Reviewed Cancer Research Program W81XWH-16-1-0329DOD Prostate Cancer Idea Development AwardNational Cancer Institute of the National Institutes of Health 1U24CA199374-01National Cancer Institute of the National Institutes of Health R01CA202752-01A1National Cancer Institute of the National Institutes of Health R01CA208236-01A1National Cancer Institute of the National Institutes of Health R01 CA216579-01A1National Cancer Institute of the National Institutes of Health R01 CA220581-01A1National Cancer Institute of the National Institutes of Health R21CA195152-01NCI NIH HHS R01 CA202752NCI NIH HHS R01 CA208236NCI NIH HHS R01 CA216579NCI NIH HHS R01 CA220581NCI NIH HHS R21 CA195152NCI NIH HHS U24 CA199374NCRR NIH HHS 1 C06 RR12463-01NCRR NIH HHS C06 RR012463Ohio Third Frontier Technology Validation FundWallace H. Coulter Foundation Program in the Department of Biomedical Engineering and the Clinical and Translational Science Award Program (CTSA) at Case Western Reserve University.
6 · The paper itself

Abstract

backgroundRadiomics or computer-extracted texture features derived from MRI have been shown to help quantitatively characterize prostate cancer (PCa). Radiomics have not been explored depth in the context of predicting biochemical recurrence (BCR) of PCa. PURPOSE: To identify a set of radiomic features derived from pretreatment biparametric MRI (bpMRI) that may be predictive of PCa BCR. STUDY TYPE: Retrospective. SUBJECTS: In all, 120 PCa patients from two institutions, I SEQUENCE: 3T, T ASSESSMENT: PCa regions of interest (ROIs) on T STATISTICAL TESTS: Wilcoxon rank-sum tests with P < 0.05 were considered statistically significant. Differences in BCR-free survival at 3 years using p

resultsDistribution statistics of co-occurrence of local anisotropic gradient orientation (CoLlAGe) and Haralick features from T DATA

conclusionRadiomic features from pretreatment bpMRI can be predictive of PCa BCR after therapy and may help identify men who would benefit from adjuvant therapy. LEVEL OF EVIDENCE: 4 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2018;48:1626-1636.

Indexed as

Diagnosis, Computer-AssistedMagnetic Resonance ImagingAgedAged, 80 and overAlgorithmsDiffusion Magnetic Resonance ImagingHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMachine LearningMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalPattern Recognition, AutomatedProstatic Neoplasmscomputer-assisted image processingmagnetic resonance imagingprojections and predictionsprostate cancerrecurrence

Identifiers

PMID29734484
PMCPMC6222024
OpenAlexW2801634535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.