Evidence map›Paper›PMID 29734398›Full record

ArticlePloS one2018

Comparison of clinical scores in their ability to detect hypoxemic severe OSA patients.

Eric Deflandre, Nicolas Piette, Vincent Bonhomme, Stephanie Degey, Laurent Cambron, Robert Poirrier, Jean-Francois Brichant, Jean Joris

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02050685 (Comparison of Different Screening Score for Hypoxemic OSA), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02050685 completednot on this map

Comparison of Different Screening Score for Hypoxemic OSA

TypeobservationalSponsorEric DEFLANDRE, MD, FCCPRan2014 to 2015Enrolled159ConditionsSleep Apnea, ObstructiveArmsAll patients incoming in the sleep study centre for a PSG
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eric DeflandreDepartment of Anesthesia, Clinique Saint-Luc of Bouge, Namur, Belgium.ORCID 0000-0001-5592-0232
Nicolas PietteDepartment of Anesthesia, University of Liege, Liege, Belgium.
Vincent BonhommeDepartment of Anesthesia, University of Liege, Liege, Belgium.
Stephanie DegeyCabinet Medical ASTES, Jambes, Namur, Belgium.
Laurent CambronSleep Laboratory Centre (CETES), University of Liege, Liege, Belgium.
Robert PoirrierSleep Laboratory Centre (CETES), University of Liege, Liege, Belgium.
Jean-Francois BrichantDepartment of Anesthesia, University of Liege, Liege, Belgium.
Jean JorisDepartment of Anesthesia, University of Liege, Liege, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere obstructive sleep apnea (sOSA) and preoperative hypoxemia are risk factors of postoperative complications. Patients exhibiting the combination of both factors are probably at higher perioperative risk. Four scores (STOP-Bang, P-SAP, OSA50, and DES-OSA) are currently used to detect OSA patients preoperatively. This study compared their ability to specifically detect hypoxemic sOSA patients.

methodsOne hundred and fifty-nine patients scheduled for an overnight polysomnography (PSG) were prospectively enrolled. The ability of the four scores to predict the occurrence of hypoxemic episodes in sOSA patients was compared using sensitivity (Se), specificity (Sp), Youden Index, Cohen kappa coefficient, and the area under ROC curve (AUROC) analyses.

resultsOSA50 elicited the highest Se [95% CI] at detecting hypoxemic sOSA patients (1 [0.89-1]) and was significantly more sensitive than STOP-Bang in that respect. DES-OSA was significantly more specific (0.58 [0.49-0.66]) than the three other scores. The Youden Index of DES-OSA (1.45 [1.33-1.58]) was significantly higher than those of STOP-Bang, P-SAP, and OSA50. The AUROC of DES-OSA (0.8 [0.71-0.89]) was significantly the largest. The highest Kappa value was obtained for DES-OSA (0.33 [0.21-0.45]) and was significantly higher than those of STOP-Bang, and OSA50.

conclusionsIn our population, DES-OSA appears to be more effective than the three other scores to specifically detect hypoxemic sOSA patients. However prospective studies are needed to confirm these findings in a perioperative setting. CLINICAL

trial registrationClinicalTrials.gov: NCT02050685.

Indexed as

Predictive Value of TestsAdultAgedBody Mass IndexFemaleHumansHypoxiaMaleMass ScreeningMiddle AgedPolysomnographyProspective StudiesRisk FactorsSensitivity and SpecificitySeverity of Illness IndexSleep Apnea, Obstructive

Identifiers

PMID29734398
PMCPMC5937788

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.