Evidence map›Paper›PMID 29734218›Full record

ArticleAIDS (London, England)2018

Depressive symptoms and problematic alcohol and other substance use in 1476 gay, bisexual, and other MSM at three research sites in Kenya.

Christine Korhonen, Makobu Kimani, Elizabeth Wahome, Fredrick Otieno, Duncan Okall, Robert C Bailey, Gary W Harper, Robert R Lorway, Monika Doshi, John Mathenge and 3 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Christine KorhonenUniversity of Washington, Seattle, Washington, USA.
Makobu KimaniKenya Medical Research Institute, Nairobi.
Elizabeth WahomeKenya Medical Research Institute, Nairobi.
Fredrick OtienoNyanza Reproductive Health Society, Kisumu, Kenya.
Duncan OkallNyanza Reproductive Health Society, Kisumu, Kenya.
Robert C BaileyNyanza Reproductive Health Society, Kisumu, Kenya.
Gary W HarperUniversity of Michigan, Ann Arbor, Michigan, USA.
Robert R LorwayUniversity of Manitoba.
Monika DoshiUniversity of Manitoba.
John MathengeHealth Options for Young Men on HIV/AIDS and STIs.
Joshua KimaniUniversity of Nairobi, Nairobi, Kenya.
Eduard J SandersKenya Medical Research Institute, Nairobi.
Susan M GrahamUniversity of Washington, Seattle, Washington, USA.
Kenya Medical Research Institute · KENyanza Reproductive Health Society · KEResearch Manitoba · CAUniversity of Manitoba · CAUniversity of Michigan–Ann Arbor · USUniversity of Nairobi · KEUniversity of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
CIHR HHP-131557Wellcome Trust 107752/Z/15/ZWellcome Trust 203077/Z/16/Z
6 · The paper itself

Abstract

objectiveInformation on mental health and substance use challenges among gay, bisexual, and other MSM (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya.

methodsSelf-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms [Patient Health Questionnaire 9 (PHQ-9)], alcohol use [Alcohol Use Disorder Identification Test (AUDIT)], and other substance use [Drug Abuse Screening Test 6 (DAST-6)]. Associations were evaluated using mixed effects Poisson regression.

resultsOf 1476 participants, 452 (31%) reported moderate-to-severe depressive symptoms (PHQ-9 ≥ 10), 637 (44%) hazardous alcohol use (AUDIT ≥ 8), and 749 (51%) problematic substance use (DAST-6 ≥ 1). Known HIV-positive status was not associated with these outcomes. Transactional sex was associated with hazardous alcohol use [adjusted prevalence ratio (aPR) 1.34, 95% confidence interval (CI) 1.12-1.60]. Childhood abuse and recent trauma were associated with moderate-to-severe depressive symptoms (aPR 1.43, 95% CI 1.10-1.86 and aPR 2.43, 95% CI 1.91-3.09, respectively), hazardous alcohol use (aPR 1.36, 95% CI 1.10-1.68 and aPR 1.60, 95% CI 1.33-1.93, respectively), and problematic substance use (aPR 1.32, 95% CI 1.09-1.60 and aPR 1.35, 95% CI 1.14-1.59, respectively).

conclusionGBMSM in rights-constrained settings need culturally appropriate services for treatment and prevention of mental health and substance use disorders, in addition to human rights advocacy to prevent abuse. Mental health and substance use screening and treatment or referral should be an integral part of programs, including HIV prevention and treatment programs, providing services to GBMSM.

Indexed as

Sexual and Gender MinoritiesAdultCross-Sectional StudiesDepressionFemaleHumansKenyaMalePrevalenceSubstance-Related DisordersYoung Adult

Identifiers

PMID29734218
PMCPMC6150184
OpenAlexW2800672488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.