Evidence map›Paper›PMID 29734045›Full record

ReviewCurrent opinion in immunology2018

Immune evasion of the CD1d/NKT cell axis.

Randy R Brutkiewicz, Laura Yunes-Medina, Jianyun Liu

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The immune system in neurological diseases: What innate-like T cells have to say.The Journal of allergy and clinical immunology · 2024
    Review
  6. The MR1/MAIT cell axis in CNS diseases.Brain, behavior, and immunity · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Ceramide and Related Molecules in Viral Infections.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Randy R BrutkiewiczDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202-5181, United States. Electronic address: rbrutkie@iu.edu.
Laura Yunes-MedinaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202-5181, United States.
Jianyun LiuDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202-5181, United States.

Funding

CDI Molecules &NKT Cells in Host DefenseR01AI046455 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI BRUTKIEWICZ, RANDY R · 2000 to 2009
$2.8M
Immune Evasion by Multiple Myeloma: Role of the Rho Kinase Signaling PathwayR01CA161178 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUTKIEWICZ, RANDY R · 2012 to 2016
$1.6M
Antigen-Presenting Function of CD1 MoleculesR01CA089026 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI BRUTKIEWICZ, RANDY R · 2002 to 2004
$725k
CD1 Molecules & NKT Cells in Host DefenseR56AI046455 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUTKIEWICZ, RANDY R · 2010 to 2010
$347k
NCI NIH HHS R01 CA089026NCI NIH HHS R01 CA161178NIAID NIH HHS R01 AI046455NIAID NIH HHS R56 AI046455
6 · The paper itself

Abstract

Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.

Indexed as

Host-Pathogen InteractionsImmune EvasionAnimalsAntigens, CD1dHumansNatural Killer T-CellsNeoplasmsSignal TransductionVirus DiseasesVirusesAntigens, CD1dCD1D protein, human

Identifiers

PMID29734045
PMCPMC6004260

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.