ArticleBrain and behavior2018
Sensor-based gait analysis in atypical parkinsonian disorders.
Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04753320 (Remote Monitoring in Progressive Supranuclear Palsy, an Alzheimer's Disease Related Dementia), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Remote Monitoring in Progressive Supranuclear Palsy, an Alzheimer's Disease Related Dementia
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- The use of digital outcome measures in clinical trials in rare neurological diseases: a systematic literature review.Orphanet journal of rare diseases · 2023Pooled it
- Construct validity of instrumented gait assessments in hospital and daily life mobility in patients with Parkinson's disease and atypical Parkinson's syndromes: an exploratory study.Journal of neurology · 2026Trial
- Moving beyond the hospital: in-depth characterization of daily-life mobility in patients with atypical Parkinsonian disorders.NPJ Parkinson's disease · 2026Article
- Pathway to Regulatory Approval of Digital Health Technologies in Progressive Supranuclear Palsy: A Scoping Review.Brain sciences · 2025Review
- Applying Wearable Sensors and Machine Learning to the Diagnostic Challenge of Distinguishing Parkinson's Disease from Other Forms of Parkinsonism.Biomedicines · 2025Article
- The efficacy of 3D gait analysis to evaluate surgical (and rehabilitation) outcome after degenerative lumbar surgery.BMC surgery · 2024Article
- Effects of physiotherapy and home-based training in parkinsonian syndromes: protocol for a randomised controlled trial (MobilityAPP).BMJ open · 2024Article
- Assessing the impact of body location on the accuracy of detecting daily activities with accelerometer data.iScience · 2024Article
- Remote at-home wearable-based gait assessments in Progressive Supranuclear Palsy compared to Parkinson's Disease.BMC neurology · 2023Article
- Can Digital Mobility Assessment Enhance the Clinical Assessment of Disease Severity in Parkinson's Disease?Journal of Parkinson's disease · 2023Article
- Balance and gait in progressive supranuclear palsy: a narrative review of objective metrics and exercise interventions.Frontiers in neurology · 2023Review
- Longitudinal Monitoring of Progressive Supranuclear Palsy using Body-Worn Movement Sensors.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Instrumented gait analysis defines the walking signature of CACNA1A disorders.Journal of neurology · 2022Article
- A Unified Local-Global Feature Extraction Network for Human Gait Recognition Using Smartphone Sensors.Sensors (Basel, Switzerland) · 2022Article
- Laboratory based assessment of gait and balance impairment in patients with progressive supranuclear palsy.Journal of the neurological sciences · 2021Article
- Characterization of gait variability in multiple system atrophy and Parkinson's disease.Journal of neurology · 2021Article
- Gait analysis may distinguish progressive supranuclear palsy and Parkinson disease since the earliest stages.Scientific reports · 2021Article
- Neuroimaging correlates of gait abnormalities in progressive supranuclear palsy.NeuroImage. Clinical · 2021Article
- Detection of Motor Dysfunction With Wearable Sensors in Patients With Idiopathic Rapid Eye Movement Disorder.Frontiers in bioengineering and biotechnology · 2021Article
- Evaluation of Three Machine Learning Algorithms for the Automatic Classification of EMG Patterns in Gait Disorders.Frontiers in neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesGait impairment and reduced mobility are typical features of idiopathic Parkinson's disease (iPD) and atypical parkinsonian disorders (APD). Quantitative gait assessment may have value in the diagnostic workup of parkinsonian patients and as endpoint in clinical trials. The study aimed to identify quantitative gait parameter differences in iPD and APD patients using sensor-based gait analysis and to correlate gait parameters with clinical rating scales. SUBJECTS AND
methodsPatients with iPD and APD including Parkinson variant multiple system atrophy and progressive supranuclear palsy matched for age, gender, and Hoehn and Yahr (≤3) were recruited at two Movement Disorder Units and assessed using standardized clinical rating scales (MDS-UPDRS-3, UMSARS, PSP-RS). Gait analysis consisted of inertial sensor units laterally attached to shoes, generating as objective targets spatiotemporal gait parameters from 4 × 10 m walk tests.
resultsObjective sensor-based gait analysis showed that gait speed and stride length were markedly reduced in APD compared to iPD patients. Moreover, clinical ratings significantly correlated with gait speed and stride length in APD patients.
conclusionOur findings suggest that patients with APD had more severely impaired gait parameters than iPD patients despite similar disease severity. Instrumented gait analysis provides complementary rater independent, quantitative parameters that can be exploited for clinical trials and care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.