Evidence map›Paper›PMID 29733456›Full record

ArticleJournal of leukocyte biology2018

Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation.

Shida Yousefi, Satish K Sharma, Darko Stojkov, Nina Germic, Salome Aeschlimann, Moyar Q Ge, Cameron H Flayer, Erik D Larson, Imre G Redai, Suhong Zhang and 4 more

Abstract read
In one paragraph

Article in Journal of leukocyte biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Eosinophil-Epithelial Cell Interactions in Asthma.International archives of allergy and immunology · 2024
    Review
  7. Implications of DNA damage in chronic lung disease.Frontiers in cell and developmental biology · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. A Novel Nonhuman Primate Model of Nonatopic Asthma.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Eosinophils as Major Player in Type 2 Inflammation: Autoimmunity and Beyond.Advances in experimental medicine and biology · 2021
    Review
  18. Article
  19. Pulmonary Surfactants: a New Therapeutic Target in Asthma.Current allergy and asthma reports · 2020
    Review
  20. Eosinophil responses during COVID-19 infections and coronavirus vaccination.The Journal of allergy and clinical immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shida YousefiUniversity of Bern, Bern, Switzerland.
Satish K SharmaUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Darko StojkovUniversity of Bern, Bern, Switzerland.
Nina GermicUniversity of Bern, Bern, Switzerland.
Salome AeschlimannUniversity of Bern, Bern, Switzerland.
Moyar Q GeUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cameron H FlayerUniversity of California, Davis, California, USA.
Erik D LarsonUniversity of California, Davis, California, USA.
Imre G RedaiUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Suhong ZhangUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cynthia J Koziol-WhiteUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Katalin KarikóUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hans-Uwe SimonUniversity of Bern, Bern, Switzerland.
Angela HaczkuUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
ENVIRONMENTAL TOXICOLOGYT32ES007059 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura S Van Winkle · 1985 to 2026
$7.9M
Mechanisms of social-stress enhanced allergic airway response in a mouse modelR01AI072197 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HACZKU, ANGELA · 2010 to 2014
$2.0M
Effects of ozone exposure on expression and function of surfactant protein DRC1ES018505 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI HACZKU, ANGELA · 2009 to 2010
$1.0M
Asthma, anxiety and GR abnormalities in non-human primatesR21AI116121 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HACZKU, ANGELA · 2015 to 2016
$448k
Effects of LGM2605 on a Primate Model of AsthmaR41AI132012 · NIAID · LIGNAMED, LLC · PI HACZKU, ANGELA, SIELECKI, THAIS MOTRIA · 2017 to 2017
$278k
NIAID NIH HHS R01 AI072197NIAID NIH HHS R21 AI116121NIAID NIH HHS R41 AI132012NIEHS NIH HHS P30 ES013508NIEHS NIH HHS RC1 ES018505NIEHS NIH HHS T32 ES007059
6 · The paper itself

Abstract

The asthmatic airways are highly susceptible to inflammatory injury by air pollutants such as ozone (O

Indexed as

AnimalsAsthmaCells, CulturedEosinophilsExtracellular TrapsHumansHypersensitivityMiceOxidants, PhotochemicalOxidative StressOzonePulmonary Surfactant-Associated Protein DOxidants, PhotochemicalOzonePulmonary Surfactant-Associated Protein Deosinophil extracellular traps (EETs)eosinophilssurfactant pulmonary-associated protein D (SP-D)

Identifiers

PMID29733456
PMCPMC6450398

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.