Evidence map›Paper›PMID 29733339›Full record

ReviewBiology of reproduction2018

Mouse models of preterm birth: suggested assessment and reporting guidelines.

Ronald McCarthy, Carmel Martin-Fairey, Dorothy K Sojka, Erik D Herzog, Emily S Jungheim, Molly J Stout, Justin C Fay, Mala Mahendroo, Jeff Reese, Jennifer L Herington and 3 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Biology of reproduction, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Modeling cerebral palsy in animals.Developmental medicine and child neurology · 2026
    Review
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  14. Genes · 2024
    Review
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  19. Article
  20. Models of necrotizing enterocolitis.Seminars in perinatology · 2023
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ronald McCarthyCenter for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.
Carmel Martin-FaireyCenter for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.
Dorothy K SojkaRheumatology Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Erik D HerzogDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, USA.
Emily S JungheimDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.
Molly J StoutDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.
Justin C FayDepartment of Biology, University of Rochester, Rochester, New York, USA.
Mala MahendrooDepartment of Obstetrics and Gynecology University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeff ReeseDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jennifer L HeringtonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Erin J PlosaDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Elaine L SheltonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sarah K EnglandCenter for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.
Vanderbilt University Medical Center · USWashington University in St. Louis · USThe University of Texas Southwestern Medical Center · USUniversity of Rochester · US

Funding

Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Detecting biochemical changes in the pregnant mouse cervix by Raman spectroscopyR01HD081121 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MAHADEVAN-JANSEN, ANITA, REESE, JOHN JEFFREY · 2014 to 2018
$1.9M
Beta 1 Integrin in the LungK08HL127102 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PLOSA, ERIN J · 2015 to 2019
$708k
Identifying Small Molecules that Regulate Uterine ContractionsR21HD088830 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HERINGTON, JENNIFER L. · 2017 to 2018
$435k
KATP channels as biomechanical sensors in the regulation of ductus arteriosus toneR21HL132805 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHELTON, ELAINE · 2016 to 2017
$417k
NHLBI NIH HHS K08 HL127102NHLBI NIH HHS R21 HL132805NICHD NIH HHS R01 HD081121NICHD NIH HHS R21 HD088830NICHD NIH HHS U54 HD087011
6 · The paper itself

Abstract

Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences. To investigate the mechanisms leading to preterm birth so as to develop prevention strategies, researchers have developed numerous mouse models of preterm birth. However, the lack of standard definitions for preterm birth in mice limits our field's ability to compare models and make inferences about preterm birth in humans. In this review, we discuss numerous mouse preterm birth models, propose guidelines for experiments and reporting, and suggest markers that can be used to assess whether pups are premature or mature. We argue that adoption of these recommendations will enhance the utility of mice as models for preterm birth.

Indexed as

AnimalsDisease Models, AnimalFemaleHumansMiceObstetric Labor, PrematurePregnancy

Identifiers

PMID29733339
PMCPMC6297318
OpenAlexW2802772708

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.