Evidence map›Paper›PMID 29733087›Full record

ArticleBrainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop)2018

Brain Cancer Imaging Phenomics Toolkit (brain-CaPTk): An Interactive Platform for Quantitative Analysis of Glioblastoma.

Saima Rathore, Spyridon Bakas, Sarthak Pati, Hamed Akbari, Ratheesh Kalarot, Patmaa Sridharan, Martin Rozycki, Mark Bergman, Birkan Tunc, Ragini Verma and 2 more

Abstract read
In one paragraph

Article in Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saima RathoreDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Spyridon BakasDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Sarthak PatiDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Hamed AkbariDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Ratheesh KalarotDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Patmaa SridharanDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Martin RozyckiDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Mark BergmanDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Birkan TuncDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Ragini VermaDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Michel BilelloDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Christos DavatzikosDepartment of Radiology, Perelman School of Medicine, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
NCI NIH HHS U24 CA189523NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Quantitative research, especially in the field of radio(geno)mics, has helped us understand fundamental mechanisms of neurologic diseases. Such research is integrally based on advanced algorithms to derive extensive radiomic features and integrate them into diagnostic and predictive models. To exploit the benefit of such complex algorithms, their swift translation into clinical practice is required, currently hindered by their complicated nature. brain-CaPTk is a modular platform, with components spanning across image processing, segmentation, feature extraction, and machine learning, that facilitates such translation, enabling quantitative analyses without requiring substantial computational background. Thus, brain-CaPTk can be seamlessly integrated into the typical quantification, analysis and reporting workflow of a radiologist, underscoring its clinical potential. This paper describes currently available components of brain-CaPTk and example results from their application in glioblastoma.

Indexed as

Computational algorithmsFiber trackingGlioblastomaImage analysisOpen-source softwareRadiomics Radiogenomics

Identifiers

PMID29733087
PMCPMC5934754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.