Trial reportTrends in hearing
Effects of Cochlear Implantation on Binaural Hearing in Adults With Unilateral Hearing Loss.
Trial report in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single-Sided Deafness and Asymmetric Hearing Loss Post-Approval Study
Cochlear Implantation in the Single-Sided Deafness in the Medicare Population
Who cites it
59 citing papers in PubMed, 116 citations in OpenAlex.
- Benefits of Cochlear Implantation in Childhood Unilateral Hearing Loss (CUHL Trial).The Laryngoscope · 2022Trial
- Subjective Benefits of Bimodal Listening in Cochlear Implant Recipients with Asymmetric Hearing Loss.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2020Trial
- Prospective Multicentric Follow-up Study of Cochlear Implantation in Adults With Single-Sided Deafness: Tinnitus and Audiological Outcomes.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2020Trial
- Cochlear Implantation in Cases of Asymmetric Hearing Loss: Subjective Benefit, Word Recognition, and Spatial Hearing.Trends in hearingTrial
- Cochlear Implantation in Adults 65 Years and Older With Single-sided Deafness and Asymmetric Hearing Loss.Otology & neurotology open · 2026Article
- A Prospective Multicenter Post-Market Study Evaluating the Safety and Effectiveness of Cochlear Implantation in Adults With Single-Sided Deafness.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Results for Adults with Asymmetric Hearing Loss Who Receive a Cochlear Implant.Audiology research · 2026Article
- Extending the Indications of Cochlear Implantation in Adults with Single-Sided Deafness. A Comprehensive Review.Journal of personalized medicine · 2026Review
- Patient-reported outcomes and speech-in-noise performance with OSIA versus other transcranial devices in unilateral and asymmetric hearing loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Influence of hearing in the non-implanted ear and age on long-term speech recognition benefit for adult cochlear implant users with asymmetric hearing loss.Frontiers in neuroscience · 2026Article
- Improvements in Perceived Abilities and Speech Recognition in Quiet and Noise for Older Adults With Single-sided Deafness or Asymmetric Hearing Loss: A Multi-center Investigation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Effects of StereoBiCROS on Speech Understanding in Noise and Quality of Life for Asymmetric Sensorineural Hearing Loss.Audiology research · 2025Article
- Platinum-Induced Ototoxicity in Pediatric Cancer Patients: A Comprehensive Approach to Monitoring Strategies, Management Interventions, and Future Directions.Children (Basel, Switzerland) · 2025Review
- Speech, Spatial, and Qualities of Hearing Scale and Tinnitus Functional Index Improvements After Cochlear Implant Surgery for Single-Sided Deafness.Laryngoscope investigative otolaryngology · 2025Article
- Unilateral Versus Bilateral Cochlear Implants in Adults: A Cross-Sectional Questionnaire Study Across Multiple Hearing Domains.Audiology research · 2025Article
- Speech Recognition and Subjective Hearing Abilities for Electric-Acoustic Stimulation Users With Unilateral Hearing Loss.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2024Article
- Cochlear Implantation in Single-Sided Deafness and Asymmetric Hearing Loss: 12 Months Follow-up Results of a European Multicenter Evaluation.The journal of international advanced otology · 2024Article
- Investigating the Utility of a Compact Loudspeaker Array for Audiometric Testing.American journal of audiology · 2024Article
- American Cochlear Implant Alliance Task Force: Recommendations for Determining Cochlear Implant Candidacy in Adults.The Laryngoscope · 2024Article
- Single-Sided Deafness and Hearing Rehabilitation Modalities: Contralateral Routing of Signal Devices, Bone Conduction Devices, and Cochlear Implants.Brain sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
A FDA clinical trial was carried out to evaluate the potential benefit of cochlear implant (CI) use for adults with unilateral moderate-to-profound sensorineural hearing loss. Subjects were 20 adults with moderate-to-profound unilateral sensorineural hearing loss and normal or near-normal hearing on the other side. A MED-EL standard electrode was implanted in the impaired ear. Outcome measures included: (a) sound localization on the horizontal plane (11 positions, -90° to 90°), (b) word recognition in quiet with the CI alone, and (c) masked sentence recognition with the target at 0° and the masker at -90°, 0°, or 90°. This battery was completed preoperatively and at 1, 3, 6, 9, and 12 months after CI activation. Normative data were also collected for 20 age-matched control subjects with normal or near-normal hearing bilaterally. The CI improved localization accuracy and reduced side bias. Word recognition with the CI alone was similar to performance of traditional CI recipients. The CI improved masked sentence recognition when the masker was presented from the front or from the side of normal or near-normal hearing. The binaural benefits observed with the CI increased between the 1- and 3-month intervals but appeared stable thereafter. In contrast to previous reports on localization and speech perception in patients with unilateral sensorineural hearing loss, CI benefits were consistently observed across individual subjects, and performance was at asymptote by the 3-month test interval. Cochlear implant settings, consistent CI use, and short duration of deafness could play a role in this result.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.