Evidence map›Paper›PMID 29732422›Full record

ArticleJournal of spine surgery (Hong Kong)2018

Developments in the treatment of Chiari type 1 malformations over the past decade.

Peter G Passias, Alexandra Pyne, Samantha R Horn, Gregory W Poorman, Muhammad B Janjua, Dennis Vasquez-Montes, Cole A Bortz, Frank A Segreto, Nicholas J Frangella, Matthew Y Siow and 5 more

Abstract read
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Pregnancy in spina bifida patients: a comparative analysis of peripartum procedures and complications.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Posterior fossa decompression for children with Chiari I malformation and hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  7. Article
  8. Article
  9. Chiari type I and hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Review
  10. Management of Chiari I malformations: a paradigm in evolution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Review
  11. Outcomes and resource utilization in surgery for Chiari I malformation in a national network of children's hospitals.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Peter G PassiasDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Alexandra PyneDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Samantha R HornDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Gregory W PoormanDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Muhammad B JanjuaDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Dennis Vasquez-MontesDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Cole A BortzDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Frank A SegretoDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Nicholas J FrangellaDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Matthew Y SiowDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Akhila SureDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Peter L ZhouDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
John Y MoonDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.
Bassel G DieboDepartment of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Shaleen N ViraDepartment of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChiari malformations type 1 (CM-1), a developmental anomaly of the posterior fossa, usually presents in adolescence or early adulthood. There are few studies on the national incidence of CM-1, taking into account outcomes based on concurrent diagnoses. To quantify trends in treatment and associated diagnoses, as retrospective review of the Kid's Inpatient Database (KID) from 2003-2012 was conducted.

methodsPatients aged 0-20 with primary diagnosis of CM-1 in the KID database were identified. Demographics and concurrent diagnoses were analyzed using chi-squared and

resultsFive thousand four hundred and thirty-eight patients were identified in the KID database with a primary diagnosis of CM-1 (10.5 years, 55% female). CM-1 primary diagnoses have increased over time (45 to 96 per 100,000). CM-1 patients had the following concurrent diagnoses: 23.8% syringomyelia/syringobulbia, 11.5% scoliosis, 5.9% hydrocephalus, 2.2% tethered cord syndrome. Eighty-three point four percent of CM-1 patients underwent surgical treatment, and rate of surgical treatment for CM-1 increased from 2003-2012 (66% to 72%, P<0.001) though complication rate decreased (7% to 3%, P<0.001) and mortality rates remained constant. Seventy percent of surgeries involved decompression-only, which increased neurologic complications compared to fusions (P=0.039). Cranial decompressions decreased from 2003-2012 (42.2-30.5%) while spinal decompressions increased (73.1-77.4%). Fusion rates have increased over time (0.45% to 1.8%) and are associated with higher complications than decompression-only (11.9%

conclusionsCM-1 diagnoses have increased in the last decade. Despite the decrease in overall complication rates, fusions are becoming more common and are associated with higher peri-operative complication rates. Commonly associated diagnoses including syringomyelia and hydrocephalus, can dramatically increase complication rates.

Indexed as

ChiariChiari malformations type 1 (CM-1)complication ratespediatricsspinal decompression

Identifiers

PMID29732422
PMCPMC5911752

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.