Evidence map›Paper›PMID 29732408›Full record

ArticleScience advances2018

A persulfidation-based mechanism controls aquaporin-8 conductance.

Stefano Bestetti, Iria Medraño-Fernandez, Mauro Galli, Michela Ghitti, Gerd P Bienert, Giovanna Musco, Andrea Orsi, Anna Rubartelli, Roberto Sitia

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Gut sulfide metabolism modulates behavior and brain bioenergetics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. HPlant, cell & environment · 2023
    Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Stefano BestettiProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.ORCID 0000-0001-5880-7200
Iria Medraño-FernandezProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.ORCID 0000-0002-7956-9915
Mauro GalliProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.
Michela GhittiBiomolecular Nuclear Magnetic Resonance (NMR) Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.ORCID 0000-0003-4059-0095
Gerd P BienertMetalloid Transport Group, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Gatersleben, Germany.
Giovanna MuscoBiomolecular Nuclear Magnetic Resonance (NMR) Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.ORCID 0000-0002-0469-2994
Andrea OrsiProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.
Anna RubartelliCell Biology Unit, IRCCS Azienda Ospedaliera Universitaria (AOU) San Martino-IST, 16132 Genoa, Italy.ORCID 0000-0001-8248-3875
Roberto SitiaProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.
Vita-Salute San Raffaele University · ITLeibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DEOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon engagement of tyrosine kinase receptors, nicotinamide adenine dinucleotide phosphate (NADPH)-oxidases release H

Indexed as

Amino Acid SequenceAquaporinsBiological TransportCell MembraneCell Membrane PermeabilityHydrogen PeroxideHydrogen SulfideModels, BiologicalMolecular ConformationOxidation-ReductionStress, PhysiologicalSulfidesaquaporin 8AquaporinsHydrogen PeroxideHydrogen SulfidepersulfidesSulfides

Identifiers

PMID29732408
PMCPMC5931763
OpenAlexW2800843922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.