Evidence map›Paper›PMID 29732381›Full record

ArticleOpen forum infectious diseases2018

Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome.

Enny S Paixao, Wei-Yee Leong, Laura C Rodrigues, Annelies Wilder-Smith

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
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  6. Article
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  10. Review
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  14. Review
  15. Article
  16. Article
  17. Article
  18. A Review:Pathogens (Basel, Switzerland) · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Enny S PaixaoInfectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-4797-908X
Wei-Yee LeongLee Kong Chian School of Medicine, Singapore, Singapore.
Laura C RodriguesInfectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Annelies Wilder-SmithInfectious Disease Epidemiology and Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.

Funding

Wellcome Trust 201870Wellcome Trust 205377
6 · The paper itself

Abstract

To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes.

Indexed as

asymptomatic prenatal infectioncongenital Zika syndromematernal infectionmicrocephalyZika

Identifiers

PMID29732381
PMCPMC5925427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.