Evidence map›Paper›PMID 29732166›Full record

ArticleConvergent science physical oncology2018

Secondary use of electronic medical records for clinical research: Challenges and Opportunities.

Wen-Wai Yim, Amanda J Wheeler, Catherine Curtin, Todd H Wagner, Tina Hernandez-Boussard

Abstract read
In one paragraph

Article in Convergent science physical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Wai YimVA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304.
Amanda J WheelerDepartment of Surgery, School of Medicine, Stanford University, 300 Pasteur Dr. Stanford CA 94305.
Catherine CurtinVA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304.
Todd H WagnerVA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304.
Tina Hernandez-BoussardDepartment of Medicine, Biomedical Informatics Research, School of Medicine, Stanford University, 1265 Welch Road, Stanford, CA 94305.

Funding

Utilizing Electronic Health Records to Measure and Improve Prostate Cancer CareR01CA183962 · NCI · STANFORD UNIVERSITY · PI HERNANDEZ-BOUSSARD, TINA · 2015 to 2019
$3.1M
Improving Quality of postoperative pain care through innovative use of electronic health recordsR01HS024096 · AHRQ · STANFORD UNIVERSITY · PI HERNANDEZ-BOUSSARD, TINA · 2015 to 2019
$1.1M
AHRQ HHS R01 HS024096NCI NIH HHS R01 CA183962
6 · The paper itself

Abstract

With increasingly ubiquitous electronic medical record (EMR) implementation accelerated by the adoption of the HITECH Act, there is much interest in the secondary use of collected data to improve outcomes and promote personalized medicine. A plethora of research has emerged using EMRs to investigate clinical research questions and assess variations in both treatments and outcomes. However, whether because of genuine complexities of modeling disease physiology or because of practical problems regarding data capture, data accuracy, and data completeness, the state of current EMR research is challenging and gives rise to concerns regarding study accuracy and reproducibility. This work explores challenges in how different experimental design decisions can influence results using a specific example of breast cancer patients undergoing excision and reconstruction surgeries from EMRs in an academic hospital and the Veterans Health Administration (VHA) We discuss emerging strategies that will mitigate these limitations, including data sharing, application of natural language processing, and improved EMR user design.

Indexed as

breast cancerElectronic medical recordmastectomystatistical modeling

Identifiers

PMID29732166
PMCPMC5933881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.