Evidence map›Paper›PMID 29732065›Full record

ArticleChemical science2018

Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism.

Jonathan Pansieri, Mohammad A Halim, Charlotte Vendrely, Mireille Dumoulin, François Legrand, Marcelle Moulin Sallanon, Sabine Chierici, Simona Denti, Xavier Dagany, Philippe Dugourd and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Halogenation of theChemistryOpen · 2020
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Jonathan PansieriUniv. Grenoble Alpes , CNRS , CEA , BIG/CBM/AFFOND , F-38000 Grenoble , France . Email: vincent.forge@cea.fr.ORCID 0000-0001-8918-9943
Mohammad A HalimInstitut Lumière Matière , UMR 5306 , Université Claude Bernard Lyon 1 , CNRS , F-69622 Lyon , France . Email: rodolphe.antoine@univ-lyon1.fr.ORCID 0000-0002-1698-7044
Charlotte VendrelyERRMECe , I-MAT FD4122 , Université de Cergy-Pontoise , F-95302 Cergy-Pontoise Cedex , France.
Mireille DumoulinEnzymology and Protein Folding , Centre for Protein Engineering , InBIOS , University of Liège , 4000 Liège 1 , Belgium.
François LegrandEnzymology and Protein Folding , Centre for Protein Engineering , InBIOS , University of Liège , 4000 Liège 1 , Belgium.
Marcelle Moulin SallanonRadiopharmaceutique Biocliniques (INSERM U1039) , Faculté de Médecine de Grenoble , F-38700 La Tronche , France.
Sabine ChiericiDépartement de Chimie Moléculaire , Univ. Grenoble Alpes , CNRS , UMR 5250 , F-38000 Grenoble , France.
Simona DentiRadiopharmaceutique Biocliniques (INSERM U1039) , Faculté de Médecine de Grenoble , F-38700 La Tronche , France.
Xavier DaganyInstitut Lumière Matière , UMR 5306 , Université Claude Bernard Lyon 1 , CNRS , F-69622 Lyon , France . Email: rodolphe.antoine@univ-lyon1.fr.
Philippe DugourdInstitut Lumière Matière , UMR 5306 , Université Claude Bernard Lyon 1 , CNRS , F-69622 Lyon , France . Email: rodolphe.antoine@univ-lyon1.fr.
Christel MarquetteUniv. Grenoble Alpes , CNRS , CEA , BIG/CBM/AFFOND , F-38000 Grenoble , France . Email: vincent.forge@cea.fr.
Rodolphe AntoineInstitut Lumière Matière , UMR 5306 , Université Claude Bernard Lyon 1 , CNRS , F-69622 Lyon , France . Email: rodolphe.antoine@univ-lyon1.fr.ORCID 0000-0001-5682-8550
Vincent ForgeUniv. Grenoble Alpes , CNRS , CEA , BIG/CBM/AFFOND , F-38000 Grenoble , France . Email: vincent.forge@cea.fr.ORCID 0000-0001-9658-6728
Université Claude Bernard Lyon 1 · FRVodafone (United Kingdom) · GBInserm · FRUniversity of Liège · BEDépartement de Chimie Moléculaire · FRErasmus Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterogeneity and polymorphism are generic features of amyloid fibers with some important effects on the related disease development. We report here the characterization, by charge detection mass spectrometry, of amyloid fibers made of three polypeptides involved in neurodegenerative diseases: Aβ

Identifiers

PMID29732065
PMCPMC5914292
OpenAlexW2785564592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.