ArticleChemical science2018
Multicolor monitoring of cellular organelles by single wavelength excitation to visualize the mitophagy process.
Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Signal-Sustained Imaging of Mitophagy with an Enzyme-Activatable Metabolic Lipid Labeling Probe.Autophagy · 2024Article
- Unveiling autophagy and aging through time-resolved imaging of lysosomal polarity with a delayed fluorescent emitter.Chemical science · 2023Article
- Brightness of fluorescent organic nanomaterials.Chemical Society reviews · 2023Review
- Interactions of Amino Group Functionalized Tetraphenylvinyl and DNA: A Label-Free "On-Off-On" Fluorescent Aptamer Sensor toward Ampicillin.Biosensors · 2023Article
- Mitochondria Targeted AIE Probes for Cancer Phototherapy.ACS omega · 2023Review
- Visualization of Mitochondria During Embryogenesis in Zebrafish by Aggregation-Induced Emission Molecules.Molecular imaging and biology · 2022Article
- An organelle-directed chemical ligation approach enables dual-color detection of mitophagy.Autophagy · 2021Article
- An aggregation-induced emission platform for efficient Golgi apparatus and endoplasmic reticulum specific imaging.Chemical science · 2021Article
- Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy.Angewandte Chemie (International ed. in English) · 2021Article
- AIE-based nanoaggregate tracker: high-fidelity visualization of lysosomal movement and drug-escaping processes.Chemical science · 2020Article
- A mitochondrial-targetable dual functional near-infrared fluorescent probe to monitor pH and HRSC advances · 2020Article
- Metal-enhancement study of dual functional photosensitizers with aggregation-induced emission and singlet oxygen generation.Nanoscale advances · 2020Article
- Ratiometric fluorescent probes based on through-bond energy transfer of cyanine donors to near-infrared hemicyanine acceptors for mitochondrial pH detection and monitoring of mitophagy.Journal of materials chemistry. B · 2020Article
- Assembly of 1Chemical science · 2019Article
- Synthesis of fluorescent polycarbonates with highly twistedRSC advances · 2019Article
- Reaction-free and MMP-independent fluorescent probes for long-term mitochondria visualization and tracking.Chemical science · 2019Article
- Novel easily available purine-based AIEgens with colour tunability and applications in lipid droplet imaging.Chemical science · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiplexed cellular organelle imaging using single wavelength excitation is highly desirable for unravelling cellular functions but remains challenging. This requires the design of organelle specific fluorophores with distinct emission but similar absorption. Herein, we present two unique aggregation-induced emission (AIE) probes to track mitochondria and lysosomes simultaneously with emission colors that can be distinguished from that of the nucleus stain Hoechst 33342 upon single wavelength excitation. Compared to conventional organelle stains, the two AIE probes have larger Stokes shifts and higher photostability, which endow them with the capability to monitor bioprocesses, such as mitophagy with strong and sustained fluorescent signals. Moreover, both probes can also stain intracellular organelles in zebrafish larvae with good cell-penetrating capabilities, showing their great potential to monitor bioprocesses
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Registered trials
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