Evidence map›Paper›PMID 29732033›Full record

ArticleCaspian journal of internal medicine2018

Comparison of preemptive effect of intravenous ketorolac versus meperidine on postoperative shivering and pain  in patients undergoing cesarean section under spinal anesthesia: A prospective, randomized, double-blind study.

Marzieh Beigom Khezri, Maryam Al-Sadat Mosallaei, Mehdi Ebtehaj, Navid Mohammadi

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Caspian journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05248152 (Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05248152 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery

TypeinterventionalSponsorUniversity Medical Centre LjubljanaRan2022 to 2024Enrolled90ConditionsPostoperative PainArmsParacetamol and Ibuprofen, Pregabalin 150mg, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marzieh Beigom KhezriDepartment of Anesthesiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Maryam Al-Sadat MosallaeiDepartment of Anesthesiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Mehdi EbtehajDepartment of Anesthesiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Navid MohammadiPreventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
Qazvin University of Medical Sciences · IRIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPain and shivering are two unpleasant problems in postoperative period. Various techniques are used to alleviate the postoperative shivering and pain. We compared the preemptive prescription of a single dose of intravenous meperidine and ketorolac on postoperative pain and shivering in patients undergoing cesarean section with spinal anesthesia.

methodsOne hundred and fifty patients who were scheduled for elective cesarean section under spinal anesthesia were randomly allocated to one of three study groups to receive intravenous ketorolac (group K), meperidine (group M) or normal saline (group P). Time to first analgesic request, analgesic requirement in the first 24 hours after surgery, body tympanic temperature, hemodynamic variables and incidence of shivering were assessed as outcome variables.

resultsThere was no significant difference between meperidine and ketorolac groups in terms of prevalence of shivering, although both groups were different from the placebo group (p<0.04). The mean time to first analgesic request was longer in group k (3.8±1.4) and groups M (3.3±1.2) than in group P (2.1±0.8) hours (p<0.001).

conclusionsThe preemptive prescription of a single dose of intravenous meperidine and ketorolac can provide a satisfying analgesia immediately after surgery and decrease shivering prevalence without any serious side effects.

Indexed as

Cesarean sectionKetorolacMeperidineShiveringSpinal anesthesia

Identifiers

PMID29732033
PMCPMC5912223
OpenAlexW2782566752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.