Evidence map›Paper›PMID 29731982›Full record

ArticleOncotarget2018

Gene-specific methylation profiles in

Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Ines Zanna, Giovanna Masala, Simonetta Bianchi, Domenico Palli, Laura Ottini

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Piera RizzoloDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Valentina SilvestriDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Virginia ValentiniDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Veronica ZelliDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Ines ZannaCancer Risk Factors and Lifestyle Epidemiology Unit, Cancer Research and Prevention Institute (ISPRO), Florence, Italy.
Giovanna MasalaCancer Risk Factors and Lifestyle Epidemiology Unit, Cancer Research and Prevention Institute (ISPRO), Florence, Italy.
Simonetta BianchiDivision of Pathological Anatomy, Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy.
Domenico PalliCancer Risk Factors and Lifestyle Epidemiology Unit, Cancer Research and Prevention Institute (ISPRO), Florence, Italy.
Laura OttiniDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male breast cancer (MBC) is a rare disease. Due to its rarity, MBC research and clinical approach are mostly based upon data derived from female breast cancer (FBC). Increasing evidence indicate that on molecular level MBC may be an heterogeneous disease different from FBC. In order to investigate whether epigenetic signatures could define molecular subgroups of MBCs, we performed promoter methylation analysis of genes involved in signal transduction and hormone signalling in

Indexed as

BRCA1/2 mutationsclinical-pathologic characteristicsmale breast cancerpromoter methylationpyrosequencing

Identifiers

PMID29731982
PMCPMC5929425
OpenAlexW2797143658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.