Evidence map›Paper›PMID 29731953›Full record

ArticleCanadian respiratory journal2018

Adrenal Insufficiency in Cystic Fibrosis: A Rare Phenomenon?

Sébastien Préville-Ratelle, Adèle Coriati, Aurélie Ménard, Isabelle Bourdeau, François Tremblay, Yves Berthiaume

Open access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sébastien Préville-RatelleClinique de fibrose kystique, Centre hospitalier de l'Université de Montréal (CHUM), 1051 rue Sanguinet, Montréal, QC, Canada H2X 0C1.ORCID 0000-0002-5014-8703
Adèle CoriatiInstitut de recherches cliniques de Montréal (IRCM), 110 Avenue des Pins, Montréal, QC, Canada H2W 1R7.ORCID 0000-0002-6442-8060
Aurélie MénardInstitut de recherches cliniques de Montréal (IRCM), 110 Avenue des Pins, Montréal, QC, Canada H2W 1R7.ORCID 0000-0003-0815-068X
Isabelle BourdeauCentre de recherche Centre hospitalier de l'Université de Montréal (CRCHUM), 900 rue Saint-Denis, Montréal, QC, Canada H2X 0A9.
François TremblayClinique de fibrose kystique, Centre hospitalier de l'Université de Montréal (CHUM), 1051 rue Sanguinet, Montréal, QC, Canada H2X 0C1.
Yves BerthiaumeClinique de fibrose kystique, Centre hospitalier de l'Université de Montréal (CHUM), 1051 rue Sanguinet, Montréal, QC, Canada H2X 0C1.ORCID 0000-0001-7422-841X
Centre Hospitalier de l’Université de Montréal · CAMontreal Clinical Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence of adrenal insufficiency (AI) in cystic fibrosis (CF) is unknown. The frequent use of glucocorticoids (inhaled or systemic) may induce the long-term suppression of the hypothalamic-pituitary-adrenal axis. Methods: We reviewed the results of adrenocorticotropic hormone (ACTH) stimulation tests done over a 10-year period to evaluate adrenal function in 69 CF patients of the CHUM CF clinic. Clinical characteristics of AI patients were compared to adrenal-sufficient (AS) patients. Results: AI was confirmed in 33 of the 69 CF patients. A higher rate of dysglycemia ( Conclusion: This study is the first to systematically examine the presence of AI in the largest cohort of CF patients studied to date with a prevalence of 8%. Patients treated with corticosteroids and those colonized with

Indexed as

Adrenal InsufficiencyAdultAgedCross-Sectional StudiesCystic FibrosisFemaleGlucocorticoidsHumansMaleMiddle AgedPrevalenceQuebecRetrospective StudiesYoung AdultGlucocorticoids

Identifiers

PMID29731953
PMCPMC5872627
OpenAlexW2791448567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.