Evidence map›Paper›PMID 29731940›Full record

ReviewOpen access Macedonian journal of medical sciences2018

Free Gingival Graft versus Mucograft: Histological Evaluation.

Zaklina Menceva, Oliver Dimitrovski, Mirjana Popovska, Spiro Spasovski, Vancho Spirov, Gordana Petrushevska

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Open access Macedonian journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03954028 (The Study on the Healing of Soft Tissue Augmentation by the Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03954028 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

The Study on the Healing of Soft Tissue Augmentation by the Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft

TypeinterventionalSponsorUniversity of FloridaRan2021 to 2022Enrolled0ConditionsGingival Recession, Generalized, Graft ReactionArmsGingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. In vitro biocompatibility of biohybrid polymers membrane evaluated in human gingival fibroblasts.Journal of biomedical materials research. Part B, Applied biomaterials · 2020
    Article
  9. Use of Mucograft Collagen MatrixFrontiers in dentistry · 2020
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zaklina MencevaDepartment of Oral Surgery, University Dental Clinical Centre St. Pantelejmon, Faculty of Dentistry, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Oliver DimitrovskiDepartment of Oral Surgery and Implantology, Faculty of Dentistry, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Mirjana PopovskaDepartment of Oral Pathology and Periodontology, Faculty of Dentistry, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Spiro SpasovskiOrdinary General Dentistry Dr. Spasovski, Skopje, Republic of Macedonia.
Vancho SpirovDepartment of Oral Surgery, University Dental Clinical Centre St. Pantelejmon, Faculty of Dentistry, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Gordana PetrushevskaInstitute of Pathology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Saints Cyril and Methodius University of Skopje · MK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe correction of the gingival recession is of esthetical and functional significance, but the tissue regeneration can only be confirmed by a histological examination.

aimThis study aims to make a comparison between the free gingival graft and the autograft. MATERIAL AND

methodsThis study included 24 patients with single and multiple gingival recessions. Twelve patients were treated with a free gingival graft and the other twelve with a micrograft. Six months after the surgical procedure, a micro-punch biopsy of the transplantation area was performed. The tissue was histologically evaluated, graded in 4 categories: immature, mature, fragmented and edematous collagen tissue. The elastic fibres were also examined and graded in three categories: with a normal structure, fragmented rare and fragmented multiplied.

resultsRegarding the type of collagen tissue that was present, there was a significant difference between the two groups of patients, with a larger number of patients treated with a micrograft showing a presence of mature tissue, compared to the patients treated with a free gingival graft. A larger number of patients in both of the groups displayed elastic fibres with a rare fragmented structure; 33.3% of the patients showed a normal structure; 50% demonstrated a normal structure.

conclusionThe patients treated with a free gingival graft showed a larger presence of fragmented collagen tissue and fragmented elastic fibres, whereas a mature tissue was predominantly present in the surgical area where a Geistlich Mucograft was placed.

Indexed as

Collagen fibresConnective tissueElastic fibresFree gingival graftGingival recessionMucograft

Identifiers

PMID29731940
PMCPMC5927503
OpenAlexW2794523916

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.