Evidence map›Paper›PMID 29731853›Full record

ArticleOncology letters2018

Targeted gene therapy of the

Shuhong Hao, Xiaoyuan Du, Yang Song, Ming Ren, Qiwei Yang, Ao Wang, Qingyu Wang, Haiyue Zhao, Zhenwu Du, Guizhen Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shuhong HaoDepartment of Hematology and Oncology, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Xiaoyuan DuDepartment of Pathology, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Yang SongDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Ming RenDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Qiwei YangDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Ao WangDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Qingyu WangThe Center of Molecular Diagnosis and Cellular Treatment for Metabolic Bone Diseases, Changchun, Jilin 130041, P.R. China.
Haiyue ZhaoResearch Center, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Zhenwu DuDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Guizhen ZhangDepartment of Orthopedics, The Second Clinical College, Jilin University, Changchun, Jilin 130021, P.R. China.
Jilin University · CNJinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of lung cancer and lung cancer-associated mortality have markedly increased worldwide, and gene-targeted therapy has emerged as a promising treatment strategy. The present study aimed to explore the targeted antitumor effect of the herpes simplex virus-thymidine kinase/human interleukin-12 (

Indexed as

fusion genegene-targeted therapylung cancersuicide genesurvival

Identifiers

PMID29731853
PMCPMC5920898
OpenAlexW2794024716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.