Evidence map›Paper›PMID 29731744›Full record

ArticleFrontiers in microbiology2018

Novel Activity of a Synthetic Decapeptide Against

Laura Giovati, Claudia Santinoli, Carlo Mangia, Alice Vismarra, Silvana Belletti, Tiziana D'Adda, Claudia Fumarola, Tecla Ciociola, Cristina Bacci, Walter Magliani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  8. Nanoformulation-Based 1,2,3-Triazole Sulfonamides for Anti-Tropical medicine and infectious disease · 2023
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  9. Review
  10. Bioactive Peptides against Human Apicomplexan Parasites.Antibiotics (Basel, Switzerland) · 2022
    Review
  11. Activity of Two Antimicrobial Peptides againstAntibiotics (Basel, Switzerland) · 2021
    Article
  12. Parasitology · 2021
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  13. Toxins · 2021
    Review
  14. Review
  15. Myrislignan Induces Redox Imbalance and Activates Autophagy inFrontiers in cellular and infection microbiology · 2021
    Article
  16. Licarin-B Exhibits Activity Against theFrontiers in cell and developmental biology · 2021
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  17. Review
  18. Review
  19. Article
  20. Myrislignan Exhibits Activities AgainstFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Laura GiovatiLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Claudia SantinoliLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Carlo MangiaDepartment of Veterinary Science, University of Parma, Parma, Italy.
Alice VismarraDepartment of Veterinary Science, University of Parma, Parma, Italy.
Silvana BellettiLaboratory of Histology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Tiziana D'AddaLaboratory of Pathological Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Claudia FumarolaLaboratory of Experimental Oncology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Tecla CiociolaLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Cristina BacciDepartment of Veterinary Science, University of Parma, Parma, Italy.
Walter MaglianiLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Luciano PolonelliLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Stefania ContiLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Laura H KramerDepartment of Veterinary Science, University of Parma, Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The killer peptide KP is a synthetic decapeptide derived from the sequence of the variable region of a recombinant yeast killer toxin-like microbicidal single-chain antibody. KP proved to exert significant activities against diverse microbial and viral pathogens through different mechanisms of action, but little is known of its effect on apicomplexan protozoa. The aim of the present study was to evaluate the

Indexed as

anti-Toxoplasma agentsapoptosiskiller peptide KPmitochondrial potentialtransmission electron microscopyTUNEL

Identifiers

PMID29731744
PMCPMC5920037
OpenAlexW2801280909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.