ArticleClinical, cosmetic and investigational dermatology2018
Histologic characterization of cellular infiltration in autoimmune subepidermal bullous diseases in a tertiary hospital in Saudi Arabia.
Article in Clinical, cosmetic and investigational dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Lymphocytic infiltration as a marker of disease severity in patients with bullous pemphigoid-A case series.Clinical case reports · 2024Article
- Article
- Diplopia and Vision Loss Associated With Presumed Systemic Lymphohistiocytic Disease: A Case Report.Clinical medicine insights. Case reports · 2022Article
- Neutrophil-rich, noncollagenous 16A domain-negative bullous pemphigoid associated with psoriasis.JAAD case reports · 2021Article
- Proteases in Pemphigoid Diseases.Frontiers in immunology · 2019Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutoimmune subepidermal bullous dermatoses have similar clinical features to those of a spectrum of immune reactants at the dermoepidermal junction (DEJ). It is difficult to obtain a precise diagnosis without an immunofluorescence assay because of their similar clinical presentations. The aim of this study was to describe the cellular cutaneous infiltration among autoimmune subepidermal bullous dermatoses. MATERIALS AND
methodsThis retrospective analysis was conducted at a hospital in Riyadh, Saudi Arabia using biopsy-based data collected from 65 patients.
resultsSpongiotic changes, neutrophils, and lymphocyte infiltrations in the epidermis differed among the subepidermal bullous diseases. The DEJ showed a difference in the extent of neutrophil infiltration. The dermis showed differences in perivascular lymphocytic infiltration, neutrophilic infiltration, eosinophilic infiltration, and dermal edema.
conclusionThe dermal and DEJ showed most of the histopathologic changes in subepidermal autoimmune bullous dermatoses.
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