Evidence map›Paper›PMID 29731625›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease

Adherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study.

Nurdan Kokturk, Mehmet Polatli, I Kivilcim Oguzulgen, Sarfraz Saleemi, Mohammed Al Ghobain, Javed Khan, Adam Doble, Luqman Tariq, Fayaz Aziz, Abdelkader El Hasnaoui

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Evidence of the association between adherence to treatment and mortality among patients with COPD monitored at a public disease management program in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Nurdan KokturkDepartment of Pulmonary Medicine, School of Medicine, Gazi University, Besevler, Turkey.
Mehmet PolatliDepartment of Pulmonary Medicine, School of Medicine, Adnan Menderes University, Aydin, Turkey.
I Kivilcim OguzulgenDepartment of Pulmonary Medicine, School of Medicine, Gazi University, Besevler, Turkey.
Sarfraz SaleemiSection of Pulmonary Medicine, Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Mohammed Al GhobainDepartment of Medicine, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Javed KhanDepartment of Medicine, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.
Adam DobleFoxymed, Paris, France.
Luqman TariqGlaxoSmithKline, Dubai, UAE.
Fayaz AzizGlaxoSmithKline, Dubai, UAE.
Abdelkader El HasnaouiGlaxoSmithKline, Dubai, UAE.
GlaxoSmithKline (India) · INAdnan Menderes University · TRKing Fahd Armed Forces Hospital · SAKing Faisal Specialist Hospital & Research Centre · SAKing Saud bin Abdulaziz University for Health Sciences · SAPulmonary Associates · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOPD affects millions of people worldwide. Poor treatment adherence contributes to increased symptom severity, morbidity and mortality. This study was designed to investigate adherence to COPD treatment in Turkey and Saudi Arabia.

methodsAn observational, cross-sectional study in adult COPD patients in Turkey and Saudi Arabia. Through physician-led interviews, data were collected on sociodemographics and disease history, including the impact of COPD on health status using the COPD Assessment Test (CAT); quality of life, using the EuroQol Five-Dimension questionnaire (EQ-5D); and anxiety and depression using the Hospital Anxiety and Depression Scale (HADS). Treatment adherence was measured using the 8-item Morisky Medication Adherence Scale (MMAS-8). Multivariate logistic regression analysis examined the predictors of non-adherence and the impact of adherence on symptom severity.

resultsFour hundred and five COPD patients participated: 199 in Turkey and 206 in Saudi Arabia. Overall, 49.2% reported low adherence (MMAS-8 <6). Of those, 74.7% reported high disease impact (CAT >15) compared to 58.4% reporting medium/high adherence (

conclusionAdherence to COPD treatment is poor in Turkey and Saudi Arabia. Non-adherence to treatment is associated with higher disease impact and reduced quality of life. Depression, age, and level of education were independent determinants of adherence.

Indexed as

Medication AdherenceAdultAge FactorsChi-Square DistributionCross-Sectional StudiesDepressionEducational StatusHealth Knowledge, Attitudes, PracticeHealth StatusHumansInterviews as TopicLogistic ModelsMental HealthMiddle AgedMultivariate AnalysisOdds Ratio8-item Morisky Medication Adherence ScaleCATCOPDCOPD Assessment TestEQ-5DEuroQol Five-Dimension questionnaireMMAS-8non-adherenceSaudi ArabiaTurkey

Identifiers

PMID29731625
PMCPMC5927343
OpenAlexW2802197918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.