Observational studyClinical interventions in aging2018
Hospitalized frail elderly patients - atrial fibrillation, anticoagulation and 12 months' outcomes.
Observational study in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Meta-analysis of Safety and Efficacy of Anticoagulation versus no Anticoagulation in Octogenarians and Nonagenarians with Atrial Fibrillation.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Pooled it
- Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Assessment and Management of Atrial Fibrillation in Older Adults with Frailty.Geriatrics (Basel, Switzerland) · 2024Review
- [Prevalence, incidence and predictive factors of atrial fibrillation in geriatric patients-A prospective observational study].Zeitschrift fur Gerontologie und Geriatrie · 2024Observational
- Direct oral anticoagulant use in hospitalized patients with atrial fibrillation across body mass index categories: design and rationale for a retrospective cohort study.Therapeutic advances in drug safety · 2024Article
- Direct Oral Anticoagulants in Special Patient Populations.Journal of clinical medicine · 2023Review
- Relationship between Pharmacological Treatment Strategy and Cognitive Function in Geriatric Patients with Atrial Fibrillation.Journal of clinical medicine · 2023Article
- Frailty and oral anticoagulant prescription in adults with atrial fibrillation: A systematic review.Aging medicine (Milton (N.S.W)) · 2023Review
- CHAAging clinical and experimental research · 2022Article
- Anticoagulation in Very Old Patients with Atrial Fibrillation (AVOPA): A Descriptive Observational Study.Drugs - real world outcomes · 2021Article
- Impact of Fall Risk and Direct Oral Anticoagulant Treatment on Quality-Adjusted Life-Years in Older Adults with Atrial Fibrillation: A Markov Decision Analysis.Drugs & aging · 2021Article
- Anticoagulant Therapy for Frail Patients with Atrial Fibrillation.Internal medicine (Tokyo, Japan) · 2021Article
- Comparison of Healthcare Resource Utilization and Costs between Rivaroxaban and Warfarin for Nonvalvular Atrial Fibrillation in a Skilled Nursing Facility Setting.Drugs & aging · 2020Article
- Determinants of anticoagulant therapy in atrial fibrillation at discharge from a geriatric ward: cross sectional study.Journal of thrombosis and thrombolysis · 2020Article
- Prevention and Treatment of Acute Stroke in the Nonagenarians and Beyond: Medical and Ethical Issues.Current treatment options in neurology · 2019Review
- Atrial Fibrillation in Older People: Concepts and Controversies.Frontiers in medicine · 2019Review
- Major Trauma in Elderly Patients: Worse Mortality and Outcomes in an Italian Trauma Center.Journal of emergencies, trauma, and shockArticle
- The 2020 CCS atrial fibrillation guidelines for pharmacists: Top 10 takeaways.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPCArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveMultiple chronic conditions and recurring acute illness are frequent among elderly people. One such condition is atrial fibrillation (AF), which increases the risk of stroke up to fivefold. The aim of this study was to investigate the prevalence of AF among hospitalized frail elderly patients, their use of anticoagulation and their 12-month outcomes. PATIENTS AND
methodsThis was a clinical observational study of acutely hospitalized frail patients over the age of 75 years. The CHA2DS2-VASc Score was used to evaluate ischemic stroke risk in patients with AF. Clinically relevant outcomes were the composite of ischemic stroke and/or bleeding within 12 months, which was considered as primary in the analysis, ischemic stroke/transient ischemic attack (TIA), mortality, bleeding and hospital care consumption. Student's
resultsThe prevalence of AF was 47%, and 63% of them were prescribed an anticoagulant. AF patients without anticoagulation were older, more often females, more often in residential care, and they had worse Mini Nutritional Assessment and activities of daily living scores. Of the patients without anticoagulation, 56% had a documented contraindication. In univariate analysis, there were significantly more events among AF patients without anticoagulation regarding the composite outcome of ischemic stroke and/or bleeding (hazard ratio [HR] 3.65, 95% CI = 1.70-7.86;
conclusionThe prevalence of AF in a hospitalized frail elderly population was 47%. Of these, 63% were prescribed anticoagulation therapy. Almost half of the patients without stroke prophylaxis had no documented contraindication. At 1 year, there were significantly more events in terms of ischemic stroke and/or bleeding among AF patients without anticoagulation therapy than among those with.
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