Evidence map›Paper›PMID 29731530›Full record

ArticleTrends in analytical chemistry : TRAC2018

Noble metal nanostructures in optical biosensors: Basics, and their introduction to anti-doping detection.

Hedieh Malekzad, Parham Sahandi Zangabad, Hadi Mohammadi, Mohsen Sadroddini, Zahra Jafari, Niloofar Mahlooji, Somaye Abbaspour, Somaye Gholami, Mana Ghanbarpoor, Rahim Pashazadeh and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in analytical chemistry : TRAC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. MoSDiagnostics (Basel, Switzerland) · 2023
    Article
  9. Green chemistry and coronavirus.Sustainable chemistry and pharmacy · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hedieh MalekzadAdvanced Nanobiotechnology and Nanomedicine Research Group (ANNRG), Iran.
Parham Sahandi ZangabadResearch Center for Pharmaceutical Nanotechnology (RCPN), Tabriz University of Medical Science (TUOMS), Tabriz, Iran.
Hadi MohammadiYoung Researchers and Elite Club, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.
Mohsen SadroddiniPolymer Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.
Zahra JafariDepartment of Food Science and Technology, College of Agriculture and Food Science, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.
Niloofar MahloojiDepartment of Chemistry, Semnan University, Semnan 35351-19111, Iran.
Somaye AbbaspourSchool of Science and Engineering, Sharif University of Technology, International Campus, Iran.
Somaye GholamiTarbiat Modares University, Tehran, Iran.
Mana GhanbarpoorTarbiat Modares University, Tehran, Iran.
Rahim PashazadehAdvanced Nanobiotechnology and Nanomedicine Research Group (ANNRG), Iran.
Ali BeyzaviKoch Institute of MIT, 500 Main Street, Cambridge MA, USA.
Mahdi KarimiCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Michael R HamblinApplied Biotechnology Research Center, Teheran Medical Sciences Branch, Islamic Azad University, Tehran Iran.

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

Nanotechnology has illustrated significant potentials in biomolecular-sensing applications; particularly its introduction to anti-doping detection is of great importance. Illicit recreational drugs, substances that can be potentially abused, and drugs with dosage limitations according to the prohibited lists announced by the World Antidoping Agency (WADA) are becoming of increasing interest to forensic chemists. In this review, the theoretical principles of optical biosensors based on noble metal nanoparticles, and the transduction mechanism of commonly-applied plasmonic biosensors are covered. We review different classes of recently-developed plasmonic biosensors for analytic determination and quantification of illicit drugs in anti-doping applications. The important classes of illicit drugs include anabolic steroids, opioids, stimulants, and peptide hormones. The main emphasis is on the advantages that noble metal nano-particles bring to optical biosensors for signal enhancement and the development of highly sensitive (label-free) biosensors. In the near future, such optical biosensors may be an invaluable substitute for conventional anti-doping detection methods such as chromatography-based approaches, and may even be commercialized for routine anti-doping tests.

Indexed as

Anti-dopingDrugs of abuseLocalized surface plasmon resonanceNoble metal nanoparticlesOptical biosensors

Identifiers

PMID29731530
PMCPMC5933885

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.