ArticleAcademic radiology2019
Performance of T2 Maps in the Detection of Prostate Cancer.
Article in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 36 citations in OpenAlex.
- Quantitative Diffusion and T2 Mapping Using RF-Modulated Phase-Based Gradient Echo Imaging.Magnetic resonance in medicine · 2026Article
- MRI-Derived Biomarkers and Radiomic Signatures for Early, Dose-Dependent Evaluation of Prostate Cancer Radiotherapy: An Exploratory Study.Journal of imaging · 2026Article
- Prostate Diffusion-weighted Imaging: Selecting the Optimal Repetition Time Using Synthetic Imaging Techniques.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Quantitative Prostate MRI, From theAJR. American journal of roentgenology · 2025Review
- Retrospectively Quantified T2 Improves Detection of Clinically Significant Peripheral Zone Prostate Cancer.Cancers · 2025Article
- Assessment of prostate cancer aggressiveness through the combined analysis of prostate MRI and 2.5D deep learning models.Frontiers in oncology · 2025Article
- DeepEMC-TMagnetic resonance in medicine · 2024Article
- Longitudinal analysis of T2 relaxation time variations following radiotherapy for prostate cancer.Heliyon · 2024Article
- Prostate Cancers Invisible on Multiparametric MRI: Pathologic Features in Correlation with Whole-Mount Prostatectomy.Cancers · 2023Article
- Advances in PET and MRI imaging of tumor hypoxia.Frontiers in medicine · 2023Review
- Retrospective T2 quantification from conventional weighted MRI of the prostate based on deep learning.Frontiers in radiology · 2023Article
- Mapping of magnetic resonance imaging's transverse relaxation time at low signal-to-noise ratio using Bloch simulations and principal component analysis image denoising.NMR in biomedicine · 2022Article
- Comparison of single-shot EPI and multi-shot EPI in prostate DWI at 3.0 T.Scientific reports · 2022Article
- MR fingerprinting of the prostate.Magma (New York, N.Y.) · 2022Review
- Emerging MR methods for improved diagnosis of prostate cancer by multiparametric MRI.Magma (New York, N.Y.) · 2022Review
- T2 mapping for the characterization of prostate lesions.World journal of urology · 2022Article
- Rapid MR relaxometry using deep learning: An overview of current techniques and emerging trends.NMR in biomedicine · 2022Review
- Magnetic resonance fingerprinting in prostate cancer before and after contrast enhancement.The British journal of radiology · 2022Article
- Validation of Prostate Tissue Composition by Using Hybrid Multidimensional MRI: Correlation with Histologic Findings.Radiology · 2022Article
- Synthetic MRI for Radiotherapy Planning for Brain and Prostate Cancers: Phantom Validation and Patient Evaluation.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
RATIONALE AND
objectivesThis study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. MATERIALS AND
methodsThe prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa underwent preoperative 3-T magnetic resonance imaging with or without endorectal coil. Two radiologists, working independently, marked regions of interests (ROIs) on PCa lesions separately on T2W images and T2 maps. Each ROI was assigned a score of 1-5 based on the confidence in accurately detecting cancer, with 5 being the highest confidence. Subsequently, the histologically confirmed PCa lesions (n = 112) on whole-mount sections were matched with ROIs to calculate sensitivity, positive predictive value (PPV), and radiologist confidence score. Quantitative T2 values of PCa and benign tissue ROIs were measured.
resultsSensitivity and confidence score for PCa detection were similar for T2W images (51%, 4.5 ± 0.8) and T2 maps (52%, 4.5 ± 0.6). However, PPV was significantly higher (P = .001) for T2 maps (88%) compared to T2W (72%) images. The use of endorectal coils nominally improved sensitivity (T2W: 55 vs 47%, T2 map: 54% vs 48%) compared to the use of no endorectal coils, but not the PPV and the confidence score. Quantitative T2 values for PCa (105 ± 28 milliseconds) were significantly (P = 9.3 × 10
conclusionsOur study shows that review of T2 maps by radiologists has similar sensitivity but higher PPV compared to T2W images. Additional quantitative information obtained from T2 maps is helpful in differentiating cancer from normal prostate tissue and determining its aggressiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.