ArticleThe Lancet. Global health2018
Cholera epidemic in Yemen, 2016-18: an analysis of surveillance data.
Article in The Lancet. Global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 3 of them syntheses that pooled it.
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94 citing papers in PubMed, 3 syntheses or guidelines pooled it, 261 citations in OpenAlex.
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- Long-Term Kinetics of Serological Antibodies againstInternational journal of environmental research and public health · 2022Pooled it
- Identifying potential emerging threats through epidemic intelligence activities-looking for the needle in the haystack?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019Pooled it
- Safety and Immunogenicity of Live Oral Cholera Vaccine CVD 103-HgR in Children and Adolescents Aged 6-17 Years.The American journal of tropical medicine and hygiene · 2020Trial
- When formal governance persists but resilience does not: health system governance and resilience in Yemen across a decade of conflict and crisis (2014-2025).BMC health services research · 2026Article
- Vibriosis-associated acute kidney injury : Incidence and outcome.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Estimating time-varying cholera transmission and oral cholera vaccine effectiveness in Haiti and Cameroon, 2021-2023.BMJ open · 2026Article
- Epidemiological characteristics and outcomes of the 2023-2024 cholera outbreak in South Yemen: a retrospective descriptive study from MSF-supported centres.BMC public health · 2026Article
- Vibrio cholerae serotype impacts pathogenicity.Nature communications · 2026Article
- Genomic characterization of clinical and environmentalFrontiers in microbiology · 2026Article
- Public health consequences of global climate change. A narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Article
- Fuzzy-fractional modeling of cholera disease using real outbreak data of angola in caputo-TFN framework.Scientific reports · 2025Article
- Providing spatial support during a major cholera outbreak in Port-au-Prince, Haiti: Creative mapping solutions in a challenging data poor environment.Spatial and spatio-temporal epidemiology · 2025Article
- Epidemiological investigation of a cholera outbreak and its socioeconomic determinants in southwest state, Somalia, January - August, 2024.Conflict and health · 2025Article
- A simulation-based policy analysis of anticipatory action for cholera outbreaks, Democratic Republic of the Congo.Bulletin of the World Health Organization · 2025Article
- Climate Change and AMR: Interconnected Threats and One Health Solutions.Antibiotics (Basel, Switzerland) · 2025Review
- Risk factors for cholera mortality: A scoping review.Tropical medicine & international health : TM & IH · 2025Article
- Cholera in conflict: outbreak analysis and response lessons from Gadaref state, Sudan (2023-2024).BMC public health · 2025Article
- Epidemiological surveillance of waterborne diseases among displaced populations: A cross-sectional study.PLOS global public health · 2025Article
34 more citing papers are in PubMed but not listed here.
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Authors and funding
26 authors at 10 institutions in 8 countries.
Funding
Abstract
backgroundIn war-torn Yemen, reports of confirmed cholera started in late September, 2016. The disease continues to plague Yemen today in what has become the largest documented cholera epidemic of modern times. We aimed to describe the key epidemiological features of this epidemic, including the drivers of cholera transmission during the outbreak.
methodsThe Yemen Health Authorities set up a national cholera surveillance system to collect information on suspected cholera cases presenting at health facilities. Individual variables included symptom onset date, age, severity of dehydration, and rapid diagnostic test result. Suspected cholera cases were confirmed by culture, and a subset of samples had additional phenotypic and genotypic analysis. We first conducted descriptive analyses at national and governorate levels. We divided the epidemic into three time periods: the first wave (Sept 28, 2016, to April 23, 2017), the increasing phase of the second wave (April 24, 2017, to July 2, 2017), and the decreasing phase of the second wave (July 3, 2017, to March 12, 2018). We reconstructed the changes in cholera transmission over time by estimating the instantaneous reproduction number, R
findingsFrom Sept 28, 2016, to March 12, 2018, 1 103 683 suspected cholera cases (attack rate 3·69%) and 2385 deaths (case fatality risk 0·22%) were reported countrywide. The epidemic consisted of two distinct waves with a surge in transmission in May, 2017, corresponding to a median R
interpretationOur analysis suggests that the small first cholera epidemic wave seeded cholera across Yemen during the dry season. When the rains returned in April, 2017, they triggered widespread cholera transmission that led to the large second wave. These results suggest that cholera could resurge during the ongoing 2018 rainy season if transmission remains active. Therefore, health authorities and partners should immediately enhance current control efforts to mitigate the risk of a new cholera epidemic wave in Yemen.
fundingHealth Authorities of Yemen, WHO, and Médecins Sans Frontières.
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