Evidence map›Paper›PMID 29731126›Full record

ReviewClinical radiology2019

Ferumoxytol-enhanced MRI in the peripheral vasculature.

E D Lehrman, A N Plotnik, T Hope, D Saloner

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Clinical radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06136806 unknown statusnot on this mapstarted 2024, after this paper: background citation

Diagnostic Performance of a Novel Ferumoxytol-Enhanced Coronary Magnetic Resonance Angiography/ Venography on Panvascular Disease: a Single-center Clinical Study.

Typeobservational_patient_registrySponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2024 to 2025Enrolled200ConditionsPanvascular DiseaseArmsFerumoxytol Enhanced Magnetic Resonance Angiography( FE-MRA);Coronary/Renal /Lower artery Arteriography, Ferumoxytol Enhanced Magnetic Resonance Venography( FE-MRV), Computed Tomography Pulmonary Angiography, Ultrasound for Lower Extremity Deep Vein.
NCT06146751 recruitingnot on this mapstarted 2023, after this paper: background citation

A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance Imaging for the Detection of Intracardiac Thrombus in Patients With Ventricular Aneurysm and After Percutaneous Ventricular Reconstruction

TypeobservationalSponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2023 to 2025Enrolled320ConditionsHeart AneurysmArmsSuperparamagnetic Iron Oxide Nanoparticles
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Guideline
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Ferumoxytol-enhanced cardiovascular magnetic resonance imaging: applications and technical advances.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

E D LehrmanDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA. Electronic address: evan.lehrman@ucsf.edu.
A N PlotnikDepartment of Radiology, University of California, Los Angeles, CA, USA.
T HopeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; Department of Radiology, Veterans Affairs Medical Center, University of California, San Francisco, CA, USA.
D SalonerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; Department of Radiology, Veterans Affairs Medical Center, University of California, San Francisco, CA, USA.
San Francisco VA Medical Center · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

MRI of Structure and Function in Assessing Hemodynamic Impact on AAA EvolutionR01HL114118 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI SALONER, DAVID A · 2014 to 2017
$1.8M
NHLBI NIH HHS R01 HL114118
6 · The paper itself

Abstract

Ferumoxytol is a promising non-gadolinium-based contrast agent with numerous varied magnetic resonance imaging applications. Previous reviews of vascular applications have focused primarily on cardiac and aortic applications. After considering safety concerns and technical issues, the objective of this paper is to explore peripheral applications for ferumoxytol-enhanced magnetic resonance angiography (MRA) and venography (MRV) in the upper and lower extremities. Separate searches for each of the following keywords were performed in pubmed: "ferumoxytol," "ultrasmall superparamagnetic iron oxide," and "USPIO." All studies pertaining to MRA or MRV in humans are included in this review. Case-based examples of various peripheral applications are used to supplement a relatively scant literature in this space. Ferumoxytol's unique properties including high T1 relaxivity and prolonged intravascular half-life make it the optimal vascular imaging contrast agent on the market and one whose vast potential has only begun to be tapped.

Indexed as

Contrast MediaFerrosoferric OxideBlood VesselsHumansMagnetic Resonance AngiographyPeripheral Vascular DiseasesTranscatheter Aortic Valve ReplacementContrast MediaFerrosoferric Oxide

Identifiers

PMID29731126
PMCPMC7437525
OpenAlexW2799892008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.