GuidelineThe Canadian journal of cardiology2018
Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children.
Registry-linked trialOpen access · greenAbstract readPractice Guideline
In one paragraph
Guideline in The Canadian journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04508985 (Management of Renin-Angiotensin-Aldosterone System Blockade in Patients Admitted in Hospital With Confirmed Coronavirus Disease), which is not on this map. Cited by 269 papers, 15 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
269citing papers in PubMed, 15 pooled it
67.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management of Renin-Angiotensin-Aldosterone System Blockade in Patients Admitted in Hospital With Confirmed Coronavirus Disease (COVID-19) Infection: The McGill RAAS-COVID-19 Randomized Controlled Trial
Who cites it
269 citing papers in PubMed, 15 syntheses or guidelines pooled it, 578 citations in OpenAlex.
- Efficacy of a Salt Substitute on the Incidence of Hypertension: A Systematic Review with Meta-Analysis.Arquivos brasileiros de cardiologia · 2026Pooled it
- Are Canadian Clinical Practice Guidelines Accounting for Adults With Multiple Chronic Diseases? A Systematic Review.Journal of evaluation in clinical practice · 2025Pooled it
- Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Standards for the Implementation, Analysis, Interpretation, and Reporting of 24-hour Ambulatory Blood Pressure Monitoring Recommendations of the Italian Society of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Guideline
- Pooled it
- Anti-hypertensive medications and risk of colorectal cancer: a systematic review and meta-analysis.Cancer causes & control : CCC · 2022Pooled it
- [Integrated Care Protocol: Hypertension].Revista medica del Instituto Mexicano del Seguro Social · 2022Guideline
- Systematic Review of Self-Measured Blood Pressure Monitoring With Support: Intervention Effectiveness and Cost.American journal of preventive medicine · 2022Pooled it
- Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Long-term effects of weight-reducing diets in people with hypertension.The Cochrane database of systematic reviews · 2021Pooled it
- Long-term effects of weight-reducing drugs in people with hypertension.The Cochrane database of systematic reviews · 2021Pooled it
- Hypertension in Children and Adolescents: A Position Statement From a Panel of Multidisciplinary Experts Coordinated by the French Society of Hypertension.Frontiers in pediatrics · 2021Pooled it
- Alcohol intake reduction for controlling hypertension.The Cochrane database of systematic reviews · 2020Pooled it
- Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.The Cochrane database of systematic reviews · 2020Pooled it
- Legacy effect of delayed blood pressure lowering drug treatment in middle-aged adults with mildly elevated blood pressure: systematic review and meta-analysis.Journal of human hypertension · 2020Pooled it
- Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-Disabling Stroke or Transient Ischemic Attack (PREVENT Trial): A Randomized Controlled Trial.Neurorehabilitation and neural repair · 2022Trial
- Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.Advances in therapy · 2022Trial
- Efficacy of Pharmaceutical Care in Patients with Type 2 Diabetes Mellitus and Hypertension: A Randomized Controlled Trial.International journal of clinical practice · 2022Trial
- Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication.American journal of hypertension · 2021Trial
- RBMJ open · 2021Trial
209 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
83 authors at 20 institutions in 3 countries.
Kara A NerenbergDivision of General Internal Medicine, Departments of Medicine, Obstetrics and Gynecology, Community Health Sciences, University of Calgary, Calgary, Alberta, Canada. Electronic address: kara.nerenberg@ucalgary.ca.
Kelly B ZarnkeO'Brien Institute for Public Health and Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Alexander A LeungDivision of Endocrinology and Metabolism, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Kaberi DasguptaDepartment of Medicine and Centre for Outcomes Research and Evaluation, McGill University and Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Sonia ButaliaDepartments of Medicine and Community Health Sciences, O'Brien Institute for Public Health and Libin Cardiovascular Institute, Cumming School of Medicine, Calgary, Alberta, Canada.
Kerry McBrienCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Kevin C HarrisDepartment of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Meranda NakhlaDepartment of Medicine and Centre for Outcomes Research and Evaluation, McGill University and Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Lyne CloutierDepartment of Nursing, Université du Québec à Trois-Rivières, Trois-Rivières, Quebec, Canada.
Mark GelferDepartment of Family Practice, University of British Columbia, Vancouver, British Columbia, Canada.
Maxime Lamarre-ClicheUniversité de Montréal, Montréal, Quebec, Canada.
Alain MilotDepartment of Medicine, Université Laval, Québec, Quebec, Canada.
Peter BolliMcMaster University, Hamilton, Ontario, Canada.
Guy TremblayCHU-Québec-Hopital St. Sacrement, Québec, Quebec, Canada.
Donna McLeanAlberta Health Services and Covenant Health, Edmonton, Alberta, Canada.
Raj S PadwalDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Karen C TranDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Steven GroverMcGill Comprehensive Health Improvement Program (CHIP), Montreal, Quebec, Canada.
Simon W RabkinVancouver Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Gordon W MoeSt Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Jonathan G HowlettDepartments of Medicine and Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada.
Patrice LindsayDirector of Stroke, Heart and Stroke Foundation of Canada, Adjunct Faculty, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Michael D HillDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Mike SharmaMcMaster University, Hamilton Health Sciences, Population Health Research Institute, Hamilton, Ontario, Canada.
Thalia FieldUniversity of British Columbia, Vancouver Stroke Program, Vancouver, British Columbia, Canada.
Theodore H WeinMcGill University, Stroke Prevention Clinic, Montreal General Hospital, Montreal, Quebec, Canada.
Ashkan ShoamaneshMcMaster University, Hamilton Health Sciences, Population Health Research Institute, Hamilton, Ontario, Canada.
George K DresserSchulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Pavel HametFaculté de Médicine, Université de Montréal, Montréal, Quebec, Canada.
Robert J HermanDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Ellen BurgessDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Steven E GrynDepartment of Medicine, Western University, London, Ontario, Canada.
Jean C GrégoireUniversité de Montréal, Institut de cardiologie de Montréal, Montréal, Quebec, Canada.
Richard LewanczukDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Luc PoirierInstitut National d'Excellence en Sante et Services Sociaux, Québec, Quebec, Canada.
Tavis S CampbellDepartment of Psychology, University of Calgary, Calgary, Alberta, Canada.
Ross D FeldmanWinnipeg Regional Health Authority and the University of Manitoba, Winnipeg, Manitoba, Canada.
Kim L LavoieUniversity of Quebec at Montreal (UQAM), Montreal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montréal, Quebec, Canada.
Ross T TsuyukiDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
George HonosCHUM, University of Montreal, Montreal, Quebec, Canada.
Ally P H PrebtaniInternal Medicine, Endocrinology and Metabolism, McMaster University, Hamilton, Ontario, Canada.
Gregory KlineDivision of Endocrinology and Metabolism, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Ernesto L SchiffrinJewish General Hospital, McGill University, Montreal, Quebec, Canada.
Andrew Don-WauchopeLifeLabs Inc, McMaster University, Hamilton, Ontario, Canada.
Sheldon W TobeUniversity of Toronto, Toronto, Ontario, and Northern Ontario School of Medicine, Sudbury, Ontario, Canada.
Richard E GilbertUniversity of Toronto, Division of Endocrinology, St Michael's Hospital, Toronto, Ontario, Canada.
Lawrence A LeiterUniversity of Toronto, Division of Endocrinology, St Michael's Hospital, Toronto, Ontario, Canada.
Charlotte JonesDepartment of Medicine, UBC Southern Medical Program, Kelowna, British Columbia, Canada.
Vincent WooUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Robert A HegeleDepartments of Medicine (Division of Endocrinology) and Biochemistry, Western University, London, Ontario, Canada.
Peter SelbyCentre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.
Andrew PipeUniversity of Ottawa Heart Institute, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Philip A McFarlaneDivision of Nephrology, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Paul OhUniversity Health Network, Toronto Rehab and Peter Munk Cardiac Centre, Toronto, Ontario, Canada.
Milan GuptaDepartment of Medicine, McMaster University, Hamilton, Ontario, and Canadian Collaborative Research Network, Brampton, Ontario, Canada.
Simon L BaconDepartment of Exercise Science, Concordia University, and Montreal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montréal, Quebec, Canada.
Janusz KaczorowskiDepartment of Family and Emergency Medicine, Université de Montréal and CRCHUM, Montréal, Quebec, Canada.
Luc TrudeauDivision of Internal Medicine, Department of Medicine, McGill University, Montréal, Quebec, Canada.
Norman R C CampbellDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Swapnil HiremathUniversity of Ottawa and the Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Michael RoereckeInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Joanne ArcandFaculty of Health Sciences, University of Ontario Institute of Technology, Oshawa, Ontario, Canada.
Marcel RuzickaDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
G V Ramesh PrasadUniversity of Toronto, Toronto, Ontario, Canada.
Michel ValléeHôpital Maisonneuve-Rosemont, Université de Montréal, Montréal, Quebec, Canada.
Cedric EdwardsDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Praveena SivapalanDivision of General Internal Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
S Brian PennerUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Anne FournierCentre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, Quebec, Canada.
Geneviève BenoitService de néphrologie, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, Quebec, Canada.
Janusz FeberChildren's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Janis DionneDepartment of Pediatrics, Division of Nephrology, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, Canada.
Laura A MageeDepartment of Women and Children's Health, St Thomas' Hospital, London, and Department of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Alexander G LoganMount Sinai Hospital, Toronto, Ontario, Canada.
Anne-Marie CôtéUniversité de Sherbrooke, Sherbrooke, Quebec, Canada.
Evelyne ReyCHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada.
Tabassum FirozDepartment of Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Laura M KuyperUniversity of British Columbia, Vancouver, British Columbia, Canada.
Jonathan Y GaborInterlake-Eastern Regional Healthy Authority, Concordia Hospital, Winnipeg, Manitoba, Canada.
Raymond R TownsendPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Doreen M RabiDivision of Endocrinology and Metabolism, Department of Medicine, University of Calgary, Calgary, Alberta, Canada; Departments of Medicine and Community Health Sciences, O'Brien Institute for Public Health and Libin Cardiovascular Institute, Cumming School of Medicine, Calgary, Alberta, Canada.
Stella S DaskalopoulouDivision of Internal Medicine, Department of Medicine, McGill University, Montréal, Quebec, Canada.
Hypertension Canada
University of Calgary · CAUniversity of British Columbia · CAMcMaster University · CASt. Michael's Hospital · CAUniversité de Montréal · CAUniversity of Ottawa · CACentre Hospitalier Universitaire Sainte-Justine · CAUniversity of Alberta · CAUniversity of Toronto · CAWestern University · CACentre for Addiction and Mental Health · CAMcGill University · CAMcGill University Health Centre · CAPopulation Health Research Institute · CAUniversity of Manitoba · CAAlberta Health Services · CABrown University · USChildren's Hospital of Eastern Ontario · CAConcordia Hospital · CAHôpital du Sacré-Cœur de Montréal · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension in adults and children. This year, the adult and pediatric guidelines are combined in one document. The new 2018 pregnancy-specific hypertension guidelines are published separately. For 2018, 5 new guidelines are introduced, and 1 existing guideline on the blood pressure thresholds and targets in the setting of thrombolysis for acute ischemic stroke is revised. The use of validated wrist devices for the estimation of blood pressure in individuals with large arm circumference is now included. Guidance is provided for the follow-up measurements of blood pressure, with the use of standardized methods and electronic (oscillometric) upper arm devices in individuals with hypertension, and either ambulatory blood pressure monitoring or home blood pressure monitoring in individuals with white coat effect. We specify that all individuals with hypertension should have an assessment of global cardiovascular risk to promote health behaviours that lower blood pressure. Finally, an angiotensin receptor-neprilysin inhibitor combination should be used in place of either an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in individuals with heart failure (with ejection fraction < 40%) who are symptomatic despite appropriate doses of guideline-directed heart failure therapies. The specific evidence and rationale underlying each of these guidelines are discussed.
Indexed as
Blood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryHypertensionAdultAntihypertensive AgentsCanadaCardiovascular DiseasesChildEvidence-Based PracticeFemaleHealth PromotionHumansMalePreventive Health ServicesRisk AssessmentAntihypertensive Agents
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04508985ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.