Evidence map›Paper›PMID 29730202›Full record

ArticleThe Journal of urology2018

Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence.

Nazema Y Siddiqui, Jonathan B Wiseman, David Cella, Catherine S Bradley, H Henry Lai, Margaret E Helmuth, Abigail R Smith, James W Griffith, Cindy L Amundsen, Kimberly S Kenton and 7 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 58 citations in OpenAlex.

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  13. Effect of lattice COWorld journal of psychiatry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Nazema Y SiddiquiDivision of Urogynecology and Reconstructive Surgery, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina. Electronic address: nazema.siddiqui@duke.edu.
Jonathan B WisemanArbor Research Collaborative for Health, Ann Arbor, Michigan.
David CellaDepartment of Medical Social Sciences, Northwestern University, Chicago, Illinois.
Catherine S BradleyDepartments of Obstetrics and Gynecology and Urology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
H Henry LaiDepartments of Surgery and Anesthesiology, Washington University School of Medicine, St. Louis, Missouri.
Margaret E HelmuthArbor Research Collaborative for Health, Ann Arbor, Michigan.
Abigail R SmithArbor Research Collaborative for Health, Ann Arbor, Michigan.
James W GriffithDepartment of Medical Social Sciences, Northwestern University, Chicago, Illinois.
Cindy L AmundsenDivision of Urogynecology and Reconstructive Surgery, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina.
Kimberly S KentonFeinberg School of Medicine, Northwestern University, Chicago, Illinois.
J Quentin ClemensUniversity of Michigan, Ann Arbor, Michigan.
Karl J KrederDepartments of Obstetrics and Gynecology and Urology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Robert M MerionArbor Research Collaborative for Health, Ann Arbor, Michigan.
Ziya KirkaliNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
John W KusekNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Anne P CameronUniversity of Michigan, Ann Arbor, Michigan.
LURN
Arbor Research Collaborative for Health · USNorthwestern University · USDuke University · USNational Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Iowa · USUniversity of Michigan–Ann Arbor · USWashington University in St. Louis · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating CenterU24DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI GRAFF, JOHN JOSEPH · 2019 to 2025
$6.9M
Phenotype of urinary symptoms and relationships with genotype, sleep and obesityU01DK097779 · NIDDK · UNIVERSITY OF CHICAGO · PI GRIFFITH, JAMES WILLIAM, KENTON, KIMBERLY SUE · 2012 to 2025
$5.7M
Advancing the Measurement and Classification of Lower Urinary Tract DysfunctionU01DK097780 · NIDDK · DUKE UNIVERSITY · PI AMUNDSEN, CINDY, JELOVSEK, JOHN ERIC · 2012 to 2025
$5.3M
University of Iowa LURN Research SiteU01DK097772 · NIDDK · UNIVERSITY OF IOWA · PI BRADLEY, CATHERINE S, KREDER, KARL J · 2012 to 2025
$5.0M
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)U01DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2013 to 2018
$4.6M
University of Washington LURN Research SiteU01DK100011 · NIDDK · UNIVERSITY OF WASHINGTON · PI YANG, CLAIRE C · 2013 to 2025
$4.5M
University of Michigan LURN Research SiteU01DK099932 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLEMENS, J. QUENTIN · 2013 to 2023
$4.4M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Second Phase StudyU01DK100017 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2013 to 2025
$3.9M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)Data CoordinatU01DK097776 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2012 to 2016
$1.7M
Epigenomics in insulin resistance associated overactive bladderK23DK110417 · NIDDK · DUKE UNIVERSITY · PI SIDDIQUI, NAZEMA Y · 2017 to 2019
$567k
NCATS NIH HHS UL1 TR001422NIDDK NIH HHS K23 DK110417NIDDK NIH HHS U01 DK097772NIDDK NIH HHS U01 DK097776NIDDK NIH HHS U01 DK097779NIDDK NIH HHS U01 DK097780NIDDK NIH HHS U01 DK099879NIDDK NIH HHS U01 DK099932NIDDK NIH HHS U01 DK100011NIDDK NIH HHS U01 DK100017NIDDK NIH HHS U24 DK099879
6 · The paper itself

Abstract

purposeWe examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. MATERIALS AND

methodsThis baseline cross-sectional analysis was performed in treatment seeking women with lower urinary tract symptoms. All participants completed the LUTS (Lower Urinary Tract Symptoms) Tool (Pfizer, New York, New York), which was used to classify women based on urinary incontinence symptoms and measure severity. The PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaire for depression, anxiety, sleep disturbance and physical function, the PSS (Perceived Stress Scale) and the IPAQ-SF (International Physical Activity Questionnaire Short Form) were administered. Multivariable regression modeling was done to assess associations with urinary symptom presence, type and severity.

resultsWe studied 510 women with a mean ± SD age of 56 ± 14 years. Of the women 82% were Caucasian, 47% were obese and 14% reported diabetes. Urinary incontinence was reported by 420 women (82.4%), including stress urinary incontinence in 70, urgency urinary incontinence in 85, mixed urinary incontinence in 240 and other urinary incontinence in 25. On adjusted analyses there was no difference in any mental health, sleep or physical function measure based on the presence vs the absence of urinary incontinence. Among women with urinary incontinence PROMIS anxiety and sleep disturbance scores were higher in those with mixed urinary incontinence than stress urinary incontinence. Increasing urinary incontinence severity was associated with higher PROMIS depression and anxiety scores, and higher PSS scores. However, higher urinary incontinence severity was not associated with a difference in sleep or physical function.

conclusionsAmong treatment seeking women with lower urinary tract symptoms, increasing urinary incontinence severity rather than the presence or type of urinary incontinence was associated with increased depression, anxiety and stress.

Indexed as

Quality of LifeAgedAge FactorsAnxietyCross-Sectional StudiesDepressionFemaleHumansIncidenceLower Urinary Tract SymptomsMental HealthMiddle AgedMultivariate AnalysisPatient Reported Outcome MeasuresPhysical FitnessRegression Analysisanxietydepressionpatient reported outcome measuresurinary bladderurinary incontinence

Identifiers

PMID29730202
PMCPMC6146022
OpenAlexW2802738176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.