Evidence map›Paper›PMID 29729808›Full record

ReviewTrends in neurosciences2018

Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models.

Yeliz Yuva-Aydemir, Sandra Almeida, Fen-Biao Gao

Open access · greenAbstract readReview
In one paragraph

Review in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Generation ofbioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. BMP/TGF-β signaling as a modulator of neurodegeneration in ALS.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  12. The progress inSmall GTPases · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yeliz Yuva-AydemirDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Sandra AlmeidaDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Fen-Biao GaoDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: fen-biao.gao@umassmed.edu.
University of Massachusetts Chan Medical School · US

Funding

Investigating Pathogenic Mechanisms of Frontotemporal Dementia Caused by Mutations in CHMP2B and TBK1R37NS057553 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2018 to 2024
$4.3M
Understanding Frontotemporal Dementia Using Drosophila and iPSC ModelsR01NS101986 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Fen-Biao Gao · 2017 to 2026
$3.6M
Prefrontal AMPA receptors in FTD PathogenesisR01NS093097 · NINDS · UPSTATE MEDICAL UNIVERSITY · PI GAO, FEN-BIAO, YAO, WEI-DONG · 2016 to 2020
$2.4M
Understanding Frontotemporal Dementia Using Drosophila and iPSC ModelsRF1NS101986 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2022 to 2022
$2.1M
NINDS NIH HHS R01 NS093097NINDS NIH HHS R01 NS101986NINDS NIH HHS R37 NS057553NINDS NIH HHS RF1 NS101986
6 · The paper itself

Abstract

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Indexed as

Amyotrophic Lateral SclerosisAnimalsC9orf72 ProteinDisease Models, AnimalDNA Repeat ExpansionDrosophilaFrontotemporal DementiaHumansInduced Pluripotent Stem CellsC9orf72 ProteinautophagyDNA damageDPR proteinnucleocytoplasmic transportRAN translationrepeat expansion

Identifiers

PMID29729808
PMCPMC6015541
OpenAlexW2802377579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.