Evidence map›Paper›PMID 29729590›Full record

Trial reportClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2018

Long term electroencephalography in preterm neonates: Safety and quality of electrode types.

Nathalie M El Ters, Amit M Mathur, Siddharth Jain, Zachary A Vesoulis, John M Zempel

Abstract readClinical Trial
In one paragraph

Trial report in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nathalie M El TersDivision of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: nathalie.elters@wustl.edu.
Amit M MathurDivision of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Siddharth JainDivision of Pediatric Neurology, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Zachary A VesoulisDivision of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
John M ZempelDivision of Pediatric Neurology, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
NEUROLOGICAL SCIENCES ACADEMIC DEVELOPMENT AWARD(INST)K12NS001690 · NINDS · WASHINGTON UNIVERSITY · PI WONG, MICHAEL · 1993 to 2018
$5.2M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS KL2 TR002346NINDS NIH HHS K12 NS001690
6 · The paper itself

Abstract

objectivesThe objective of this study was to compare gold cup and hydrogel electrodes for frequency of electrode replacement, longevity of the original electrodes after initial placement, recording quality, and skin safety issues in long-term EEG studies in preterm neonates.

methodsWe performed a prospective trial with newborns born at ≥23 weeks and ≤30 weeks of gestational age (GA). Two mirror image EEG electrode arrays were utilized on consecutive subjects, where gold cup electrodes alternated with hydrogel electrodes.

resultsOur sample included 50 neonates with mean GA of 27 (±1) weeks. The mean recording time was 84 (±15) hours. No difference was present in the frequency of replacement of either type across the total recording time (p = 0.8). We collected the time at which electrodes were first replaced, and found that hydrogel electrodes showed a longer uninterrupted recording time of 28(±2) hours vs. 20(±2) hours for gold cup electrodes (p = 0.01). Recording quality was similar in either type (p = 0.2). None of the patients experienced significant skin irritation from a discrete electrode.

conclusionLong-term EEG studies can be performed with either gold cup or hydrogel electrodes, validating the safety and quality of both electrode types. SIGNIFICANCE: Hydrogel electrodes are a reasonable alternative for use in long-term EEG studies in preterm neonates.

Indexed as

ElectrodesElectroencephalographyFemaleGoldHumansHydrogel, Polyethylene Glycol DimethacrylateInfant, NewbornInfant, PrematureMaleProspective StudiesScalpTime FactorsGoldHydrogel, Polyethylene Glycol DimethacrylateElectrodeElectroencephalographyGold cupHydrogelQualitySafety

Identifiers

PMID29729590
PMCPMC6211181
OpenAlexW2789493287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.