ArticleThe Science of the total environment2018
Rapid experimental measurements of physicochemical properties to inform models and testing.
Article in The Science of the total environment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- An Assessment of the Ocular Toxicity of Two Major Sources of Environmental Exposure.International journal of environmental research and public health · 2024Article
- Application of read-across methods as a framework for the estimation of emissions from chemical processes.Clean technologies and recycling · 2023Article
- Considerations for Applying Route-to-Route Extrapolation to Assess the Safety of Oral Exposure to Substances.Biomolecules · 2022Article
- The chemical landscape of high-throughput new approach methodologies for exposure.Journal of exposure science & environmental epidemiology · 2022Review
- Current status and future directions for a neurotoxicity hazard assessment framework that integratesComputational toxicology (Amsterdam, Netherlands) · 2022Article
- Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods.Frontiers in pharmacology · 2022Article
- Predicting compound amenability with liquid chromatography-mass spectrometry to improve non-targeted analysis.Analytical and bioanalytical chemistry · 2021Article
- Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.Regulatory toxicology and pharmacology : RTP · 2021Article
- Assessing Human Exposure to SVOCs in Materials, Products, and Articles: A Modular Mechanistic Framework.Environmental science & technology · 2021Review
- The using of the Index of Ideality of Correlation (IIC) to improve predictive potential of models of water solubility for pesticides.Environmental science and pollution research international · 2020Article
- New Approach Methodologies for Exposure Science.Current opinion in toxicology · 2019Article
- Prediction of Partition Coefficients of Environmental Toxins Using Computational Chemistry Methods.ACS omega · 2019Article
- OPERA models for predicting physicochemical properties and environmental fate endpoints.Journal of cheminformatics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The structures and physicochemical properties of chemicals are important for determining their potential toxicological effects, toxicokinetics, and route(s) of exposure. These data are needed to prioritize the risk for thousands of environmental chemicals, but experimental values are often lacking. In an attempt to efficiently fill data gaps in physicochemical property information, we generated new data for 200 structurally diverse compounds, which were rigorously selected from the USEPA ToxCast chemical library, and whose structures are available within the Distributed Structure-Searchable Toxicity Database (DSSTox). This pilot study evaluated rapid experimental methods to determine five physicochemical properties, including the log of the octanol:water partition coefficient (known as log(K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.